Dimethylcarbamoyl chloride

Beryllium and certain compounds Cadmium and certain compounds Carbon tetrachloride Chlorambucil Cyclophosphamide Dimethylcarbamoyl chloride Dimethyl sulphate Ethylene oxide Iron dextran... 

The reaction of 4-lithiodibenzofuran with 0-methylhydroxylamine provides a synthesis of the 4-amino compound, and reaction with iodine leads to the iodo compound. The reactions of 4-lithiodibenzofuran with tributyl borate,diphenyl disulfide, A,A/-dimethylcarbamoyl chloride, and cyanuric chloride have been studied. 

Pyridol, Pyrrolidine, Formaldehyde, Pyridine, Dimethylcarbamoyl chloride. Sodium carbonate. Chloroform, Sodium sulfate. Sodium sulfate, Tetrahydrofuran, fl,fl -Dibromo-4,4 -biacetophenone, Ethanol, Charcoal, Ethyl ether Ethyl alcohol, 3-Dimethylcarbomoxydunethylanaline, Dibromo-4,4 -biacetophenone, Charcoal, Ethyl acetate Bleach, Ammonia... 

Dimethoxybenzidine p-Dimethylaminoazobenzene p-Dimethylammobenzenediazo-sodium sulfonate trans-2-PDimethylamino) methylamino]-5-[2-5-mtro-2-fuiyl) vinylhl,3,4-oxadiazole 3,3 -Dimethylbenzidine Dimethylcarbamoyl chloride ... 

Reaction of dimethylcarbamoyl chloride with p-methoxyphenol to give p-methoxyphenol iV,iV-dimethylcarbamate [27]. 

Benz(a)pyrene 2,4-Diaminotoluene Dimethylcarbamoyl chloride 1,1-Dimethylhydrazine (and salts)... 

Dimethylcarbamoyl chloride has been produced since 1961. It has been used as an intermediate in the manufacture of a number of pharmaceuticals and pesticides (lARC, 1976). 

Dimethylcarbamoyl chloride was tested for carcinogenicity by skin application and by subcutaneous and intraperitoneal injection in female mice of one strain it induced local tumours (lARC, 1976). 

A group of 50 male Sprague-Dawley rats was treated by whole-body exposure to an atmosphere of 1 ppm [4.4 mg/m- ] dimethylcarbamoyl chloride for 6 h per day on five days per week for six weeks (i.e.. 30 exposures). The experiment included two chamber control groups, each of 150 rats. The incidence of nasal cancer corrected for mortality at 480 and 600 days in the exposed group was 12% and 17%, respectively (Snyder et al., 1986). [This experiment was not fully reported.]... 

Mouse. A group of 50 female ICR/Ha Swiss mice was treated by topical application with 2 mg dimethylcarbamoyl chloride in 0.1 mL acetone three times per week for up to 615 days. Three control groups, each of 50 mice, received acetone only for 575-665 days. No skin tumours arose in the control groups, whereas 32/50 mice in the treatment group developed tumours at the site of administration. Time to first tumour was 350 days and the tumours were identified as 1 papilloma, 27 squamous carcinomas and 4 kerato-acanthomas (Van Duuren et al., 1987). 

In the same study as the previous skin application experiment, 50 female ICR/Ha Swiss mice were treated by topical application with 5 mg dimethylcarbamoyl chloride in 0.1 mL... 

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