Differential sticking

The advantages of drilling with emulsion muds rather than with water-base muds are (1) higher drilling rate, (2) reduction in drill pipe torque and drag, (3) less bit balling, and (4) reduction in differential sticking. 

To prevent differential sticking across depleted sands stabilizers are placed throughout the drill collar string. The area of contact between drill collars and hole is reduced, thus reducing the sticking force. 

Differential sticking occurs when the pipe is standing still and is pressed against the mud cake of a highly overbalanced formation. 

Differential pressure sticking occurs when the drill pipe becomes imbedded in the mud wall cake opposite a permeable zone. The difference between the hydrostatic pressure in the drill pipe and the formation pressure holds the pipe in place, resulting in a sticking pipe. Differential sticking may be prevented, and a stuck drill bit may be freed, using an oil-mud or an oil- or water-based surfactant composition. 

CeUulosic fibers, powdered limestone, gHsonite, and asphalt are frequently added to both water and oH muds at levels of 10 to 25 kg/m (4—10 lb /bbl) when high differential pressures are encountered to control seepage losses to the formation. This treatment also is used to improve the quaHty of the mud filter cake to reduce the chance of differential pressure sticking. 

Square drill collars are used to increase the stiffness of the drill string and are recommended for drilling in crooked hole areas. The spiral type of drill collar is used for drilling formations in which the differential pressure can cause sticking of drill collars. The spiral grooves on the drill collar side reduce the area of contact between drill collar and wall, which considerably reduces the sticking force. 

Although we will stick to the IL-6 gene, it should be mentioned at the side that two other RNA polymerases exist in mammalian cells responsible for the synthesis of RNA molecules, which are not translated into proteins ribosomal (rRNA), transfer (tRNA), small nuclear (snRNA), small nucleolar (snoRNA), and some of the recently discovered microRNAs and piRNAs. These RNA molecules act in the process of translation and mRNA turnover. Micro and piRNAs are probably extremely important in the definition of stem cells and of differentiation programs. Some of them are synthesized by RNA polymerase II. 

Figure 7.5. Sticking coefficients along with differential heats of adsorption as measured by microcalorimetry for ethylene and acetylene on Rh(lOO). [Adapted from R. Kose, W.A. Brown and D.A. King, Chem. Rhys. Lett. 311 (1999) 109.]...

Because commodity and fine chemicals tend to be purchased on the basis of their chemical composition alone, they are undifferentiated. For example, there is nothing to choose between 99.9% benzene made by one manufacturer and that made by another manufacturer, other than price and delivery issues. On the other hand, specialty chemicals tend to be purchased on the basis of their effect or function and are therefore differentiated. For example, competitive pharmaceutical products are differentiated according to the efficacy of the product, rather than chemical composition. An adhesive is purchased on the basis of its ability to stick things together, rather than its chemical composition and so on. 

Cycled Feed. The qualitative interpretation of responses to steps and pulses is often possible, but the quantitative exploitation of the data requires the numerical integration of nonlinear differential equations incorporated into a program for the search for the best parameters. A sinusoidal variation of a feed component concentration around a steady state value can be analyzed by the well developed methods of linear analysis if the relative amplitudes of the responses are under about 0.1. The application of these ideas to a modulated molecular beam was developed by Jones et al. ( 7) in 1972. A number of simple sequences of linear steps produces frequency responses shown in Fig. 7 (7). Here e is the ratio of product to reactant amplitude, n is the sticking probability, w is the forcing frequency, and k is the desorption rate constant for the product. For the series process k- is the rate constant of the surface reaction, and for the branched process P is the fraction reacting through path 1 and desorbing with a rate constant k. This method has recently been applied to the decomposition of hydrazine on Ir(lll) by Merrill and Sawin (35). 

On a reverse-phase column, separation occurs because each compound has different partition rates between the solvent and the packing material. Left alone, each compound would reach its own equilibrium concentration in the solvent and on the solid support. However, we upset conditions by pumping fresh solvent down the column. The result is that components with the highest affinity for the column packing stick the longest and wash out last. This differential washout or elution of compounds is the basis for the HPLC separation. The separated, or partially separated, discs of each component dissolved in solvent move down the column, slowly moving farther apart, and elute in turn from the column into the detector flow cell. These separated compounds appear in the detector as peaks that rise and fall when the detector signal is sent to a recorder or computer. This peak data can be used either to quantitate, with standard calibration, the amounts of each material present or to control the collection of purified material in a fraction collector. 

Figure 1 Schematic diagram of a molecular beam machine. A gas at elevated pressure emanates from an orifice. The gas stream is collimated in three differential pumping stages to reduce the gas load on the target chamber. Only the part of the gas stream that reaches the target though all collimators is indicated as shaded. In the UHV target chamber a crystal is positioned in the beam path. The pressure and the target chamber and particles reflected or desorbed from the sample surface are detected by particle detectors. Inert beam flags can be moved into the beam to determine the beam intensity and the sticking coefficient. From Kleyn [22],...

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