Dichloro toluene

The submitters prepared o-chlorohydrocinnamonitrile by the following procedure. Ethyl cyanoacetate (3040 g., 27 moles) was added to a solution of 140 g. (6.1 g. atoms) of sodium in 4 1. of absolute ethanol, followed by 970 g. (6 moles) of o.a-dichloro-toluene (Eastman Organic Chemicals), to afford 890 g. (63%) of ethyl 2-(o-chlorobenzyl)cyanoacetate,2 b.p. 117-123° (0.03 mm.). Hydrolysis of this material in 2 1. of 10% aqueous sodium hydroxide at room temperature gave a quantitative yield (790 g.) of 2-(o-chlorobenzyl)cyanoacetic acid, m.p. 129-132° without recrystallization. Decarboxylation of 750 g. of the acid in 750 ml. 

An interesting variation in reactivity has also been shown20 in the carbocyclic series on reaction of Schiff s base derived from aniline and p-chlorobenzaldehyde with a number of isomeric dichlorotoluenes. 2,4-Dichlorotoluene yields only the expected stilbene 2,5-dichloro-toluene, according to reaction conditions and molar ratios, gives either the stilbene or 1,2,3-triarylpropane, whereas 2,6-dichlorotoluene yields only the addition product 24. 

In the reaction of SO with halobenzenes the correlation of the rate constants with the Hammett parameters gave values of -1.2 and -1.6 with halotoluenes. Studies on product distribution in substituted toluenes have shown that H atom abstraction from -CH3 group is an additional reaction pathway, especially in toluenes containing substituent at tw-positions (e.g. 4-chlorotoluene and 3,4- dichloro toluene). 

Several routes are feasible for the synthesis of dichlobenil, the key intermediate generally being 2,6-dichlorotoluene, rather difficult to prepare. 2,6-Dichloro-toluene cannot by obtained by the direct chlorination of toluene. 

Beilstein Handbook Reference) AI3-14885 Benzene, 1-chloro-2-(chloromethyl)- BRN 0471700 1-Chloro-2-(chloromethyl)benzene 2-Chlorobenzyl chloride a,2-Dichlorotoluene a,o-Dichlorotoluene EINECS 210-258-8 NSC 8446 o-Chlorobenzyl chloride Ortho-a-dichlorotoluene Toluene, a,o-dichloro- Toluene, o,a-dichloro-. Liquid mp = -17° bp = 217° d° = 1.2699 Am = 271, 278 nm (s = 339, 263, MeOH) insoluble in H2O, slightly soluble in EtOH, CCU, soluble in CS2, very soluble in Et20, CeHe, AcOH,... 

AI31S331 Benzenesulfonamide, N,N-dlchloro-4-methyl- Benzyl p-sulfondichloramide Dichloramine T EINECS 207-462-4 N,N-Dichloro-p-toluolsulfonaraide N,N-Oichloro-p-toluenesutfonamide N,N-Dichloro-toluene-4-sulphonamide NSC 1130 p-Toluene-sulfonamlde, N,N-dichloro- p-Toluenesulfone dichlor-amide Perakhvin. Sulfonamide antibiotic. Used as a disinfectant gennicide and antibacterial. Prisms mp = 83" hn - 228, 274 nm (MeOH) insoluble in H2O, soluble in EtOH, Et20, CeHe, CCI4, CHCI3, AcOH, petroleum ether. Shell. 

Dichloro-7-methoxy acridine may be prepared by the oxidation of 2,4-dichloro toluene and treating the resulting acid with 4-amino anisole at 220°C in the presence of KOH and w-butanol the additional compound when reaeted with either POCI3 or SOCI2 undergoes cyclization. One mole each of the side chain and the acridine residue get eondensed to yield the mepacrine base which on treatment with hydrochloric acid gives the offieial eompound. 

Benzene, 2-chlorophenol, 2,4-dichloro-toluene Silicone tubing Kolb andWilderer, 1995... 

The batch chlorination of toluene (with continuous CI2 flow) was studied in a BCR by Lohse et al. [10]. At low catalyst concentrations (FeCl3) and in the presence of trace impurities of water the reaction takes place in the slow reaction regime. The chlorination of toluene (T) and the consecutive chlorination of monochloro toluene to dichloro toluene... 

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