Dibenzoylmethane sunscreens

Topical medications useful in protecting against sunlight contain either chemical compounds that absorb ultraviolet light, called sunscreens, or opaque materials such as titanium dioxide that reflect light, called sunshades. The three classes of chemical compounds most commonly used in sunscreens are p-aminobenzoic acid (PABA) and its esters, the benzophenones, and the dibenzoylmethanes. 

Cosmetic products that are photoallergenic include fragrances, such as musk ambrette and 6-methylcoumarin, and sunscreens (e.g., para-aminobenzoic acid and its derivatives, benzophenones, dibenzoylmethanes).17 Oil of bergamot, previously a popular ingredient in fragrances, has now been eliminated from most perfumes due to its phototoxic properties.24... 

Analytical methods for the determination of sunscreen agents by gas chromatography-mass spectrometry (GC/MS) were published by Ternes et al. [374], Kazuo et al. [375] and Ro et al. [376]. The photostability and photoreactivity of 4-isopropyldibenzoylmethane (IDEM) and 4-ferf.butyl-4 -methoxy-dibenzoylmethane (TDM) was recently investigated by Schwack and Rudolph [377]. 

Photoallergic responses to sunscreen products represent an area where chemical components not known to produce dermal allergic responses are activated by solar radiation to produce ACD. I45 46 It is hypothesized here that in these instances, electromagnetic radiation may activate the skin to adsorb and/or absorb species that do not so react without the incident radiation. Alternatively, the molecular species themselves are excited by the radiation to molecular states that make them more reactive to skin. Chemicals exhibiting photoallergic contact dermatitis include oxybenzone, butyl methoxy dibenzoylmethane, methoxycinnamate, and benzophenone—all molecules that are readily photoexcitedJ45 ... 

The chemical sunscreens approved for OTC use in the United States are classified into seven classes aminobenzoates (previously known as PABA and PABA derivatives), salicylates, cinnamates, benzophenones, an-thranilates, dibenzoylmethane derivatives, and one miscellaneous chemical (phenyl-ben-... 

Synonyms Eusolex 8020 i-[4-(i-methylethyl)phenyl]-3-phenyl-i,3-propanedione i-(4-isopropylphenyl)-3-phenyl-i,3-propandione Uses UV-A absorbing agent in sunscreen cosmetic creams, lotions, lipsticks, sun oils, etc. ISOPROPYL DIBENZOYLMETHANE A... 

CT SUNSCREENS.<(dihydroxypropoxy)dibenzoylmethanes as ultraviolet absorbents for>/esters... 

P. 150639-31-9-P prepn and Claisen condensation of Sunscreens (dihydroxypropoxy)dibenzoylmethanes as UV absorbents for... 

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