Diabetic keratopathy

CT-112 (aldose reductase inhibitor) Senju Japan Diabetic keratopathy Phase II... 

Infectious crystalline keratopathy developed in a 73-year-old woman with noninsulin-dependent diabetes... 

There are many other causes of RCE, but they occur much less frequently. Among these causes are chemical or thermal burns, herpes simplex keratitis, neuroparalytic keratitis, bullous keratopathy, severe dry eyes, nocturnal lagophthalmos, diabetes mellitus, meibomian gland dysfunction, ocular rosacea, and Alport syndrome. Approximately 5% to 30% of RCEs occur spontaneously without any known predisposing fector. 

Infectious crystalline keratopathy developed in a 73-year-old woman with noninsulin-dependent diabetes mellitus after the use of topical prednisolone 1% eye-drops, for conjunctival injection over 12 months (SEDA-20, 372) (60). 

A heavier-than-water fluorinated silicone oil was used in the treatment of 30 selected cases of complicated retinal detachment due to proliferative vitreoretinopathy (n = 19), proliferative diabetic retinopathy with traction detachment (n = 2), giant retinal tears (n = 5), ruptured globe with retinal detachment (n = 2), massive choroidal effusion with retinal detachment (n = 1), and acute retinal necrosis with retinal detachment (n = 1) (13). Initial retinal reattachment was achieved in all cases. Complications included redetachment (n = l), cataract (n = 6), raised intraocular pressure (n = 4), hypotony (n = 4), keratopathy (n = 3), uveitis sjme-chia formation (n = 3), phthisis (n = 2), choroidal hemorrhage (n — 1), and vitreous hemorrhage n = 1). 

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