Retinal reattachment

A heavier-than-water fluorinated silicone oil was used in the treatment of 30 selected cases of complicated retinal detachment due to proliferative vitreoretinopathy (n = 19), proliferative diabetic retinopathy with traction detachment (n = 2), giant retinal tears (n = 5), ruptured globe with retinal detachment (n = 2), massive choroidal effusion with retinal detachment (n = 1), and acute retinal necrosis with retinal detachment (n = 1) (13). Initial retinal reattachment was achieved in all cases. Complications included redetachment (n = l), cataract (n = 6), raised intraocular pressure (n = 4), hypotony (n = 4), keratopathy (n = 3), uveitis sjme-chia formation (n = 3), phthisis (n = 2), choroidal hemorrhage (n — 1), and vitreous hemorrhage n = 1). 

Pharmacologic Retinal Reattachment with INS37217 (Denufosol Tetrasodium), a Nucleotide P2Y2 Receptor Agonist... 

Pharmacologic Retinal Reattachment with Denufosol Tetrasodium... 

Improve the time course for retinal reattachment in macular translocation surgery (26,27). 

Maminishkis A, Jalickee S, Blaug SA, et al. The P2Y2 receptor agonist INS37217 stimulates RPE fluid transport in vitro and retinal reattachment in rat. Invest Ophthalmol Vis Sci 2002 43 3555-3566. 

Wilkinson CP, Rice TA. Results of retinal reattachment surgery. In Craven L, ed. Michels Retinal Detachment. St. Louis Mosby, 1997 935-972. 

No serious systemic or ocular complications were observed, and retinal reattachment was achieved in 60% of patients postoperatively. The number of patients studied was small. However, the authors believed this therapy resulted in an improved success rate compared with other studies of the reattachment rate following surgery for advanced PVR without use of silicone oil and that the reattachment rate was comparable with the reattachment rate achieved in studies using silicone oil tamponade (47). 

Ophthalmology Corneal Graft Tape or Retinal Reattachment Eve Shield... 

Chen T, Janjua R, McDermott MK, Bernstein SL, Steidl SM, Payne GF (2006) Gelatin-based biomimetic tissue adhesive. Potential for retinal reattachment. J Biomed Mater Res B Appl Biomater 77 416-422... 

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