Di-2-pyridyl ketone

A sensitive method for the flow injection analysis of Cu + is based on its ability to catalyze the oxidation of di-2-pyridyl ketone hydrazone (DPKH) by atmospheric oxygen. The product of the reaction is fluorescent and can be used to generate a signal when using a fluorometer as a detector. The yield of the reaction is at a maximum when the solution is made basic with NaOH. The fluorescence, however, is greatest in the presence of HCl. Sketch an FIA manifold that will be appropriate for this analysis. 

Amine complexes stabilized with phosphine ligands of the type [AuL(PR3)]+ have been obtained for L = bipy,2310 phen,2310,231 quinoline,23 1 acridine,2311 benzo[h]quinoline,2311 naphthyr-idine (388)2311 2,2 -biquinoline,2311 di-2-pyridyl-ketone,2311 di-2-pyridylamine,2311 2-(2-pyridyl)-benzimidazole, 2311 ferrocenylpyridine, 2-nitroaniline,2312 4-methoxyaniline,2312 NHPh2, 2 NHEt2,2312 NMe3,2312 quinuclidine,2313 NEt3,2314 2-aminothiazoline,2315 histidine,2316... 

Amino acids accelerate and proteins retard the rate of Cu(II)-catalyzed oxidation of di-2-pyridyl ketone hydrazone (173) yielding fluorescent compounds. This has been applied for the analysis of amino acids and proteins378. 

Group I includes all of the diketones studied and the following monoketones acetone, 3,3,5,5-tetramethylcyclohexanone, benzophenone, 2-benzoylpyridine, and di-2-pyridyl ketone. This group is characterized by short phosphorescence lifetimes in both the pure solvent glasses and adsorbed in the polar silica gel-solvent matrices, and by an increase in the energy of the emitting... 

It has been found that di-2-pyridyl ketone (dpk) and reagents such as pz, MeNH2, NH3 and PhNHNH2 react together in aqueous solution in the presence of hydrated Ni(N03)2 affording tridentate ligands of the type (XV Table 101) which coordinate to nickel(II) in the octahedral complexes [NiL2](N03)2.2 6... 

Di-2-pyridyl ketone complexes to Zn2+ in an N,N-chelate fashion, while the keto group is present in the form of the geminal diol. In basic solution, this latter group is ionized, leading to A, O-coordination by the ligand.529... 

Another flow injection method coupled with catalytic fluorimetric detection was described for EDTA [39]. The method is based on the catalytic inhibition effect of EDTA on the catalytic action of Cu(II) on the oxidation of di-2-pyridyl ketone hydrazone by H2O2. Concentrations of 0.4-2 pg/mL of EDTA could be determined. 

Organotin complexes of di(2-pyridyl) ketone 2-thenoylhydrazone, 1 and 2, with 6- and 5-coordinated tin atom are less active than the parent organotins67,68. Compound 2 showed good results in tests against Bacillus subtilis, Staphylococcus aureus and also toward several Bacilli with minimum inhibitory concentration ranging from 1.5 to 3 pgml-167. At the same time this complex is devoid of DNA-damaging activity in the Bacillus subtilis rec-... 

Zn(acac)2(OH2)l reacts with Hpko (di-2-pyridyl ketone oxime) and NPLjPFe to afford NH4[Zn5(0-acac)2(pko)6](PF6)3 and [GaMe2(Fgacac)] reacts with py to give [GaMe2 (O-FeacacXpy)] . 

Cu2l2(PPh3)2(dpk)], and (Cu4l4(dpk)3] (dpk di-2-pyridyl ketone) in the solar energy storage reaction, norbornadiene/ quadricyclane. ... 

Oxalic dihydrazide (1.18 g, 10.0 mmol) was added to di-2-pyridyl ketone (3.68 g, 20.0 mmol) in methanol (100mL), and then the mixture was refluxed for lOh. A pale yellow solid was obtained, which was filtered off, washed with methanol, and dried under vacuum (yield 3.38 g, 75%). The details for making other ligands of Type 5 and Type 6 can be found in the related references. 

Hydroxylamine (NH2OH) can be determined by its colour reaction with di(2-pyridyl) ketone guanylhydrazone [113]. It can also be determined in an indirect method by its reaction with biacetyl to give dimethylglyoxime, which then reacts with Ni(II) [114]. The FIA technique has been applied in the determination of NH2OH with the use of ferrozine [115]. A review has been given of methods used for the determination of hydrazine [116]. 

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