Di isopropyl amine

Peggion E, Cosani A, Mattucci AM, Scoffone E (1964) Polymerization of gamma-ethyl-L-glutamate-N-carboxyanhydride initiated by Di-N-butyl and Di-isopropyl amine. Biopolymers 2 69-78... 

A number of other types of chiral auxiliaries have been employed in enolate alkylation. Excellent results are obtained using amides of pseudoephedrine. Alkylation occurs anti to the a-oxybenzyl group.93 The reactions involve the Z-enolate and there is likely bridging between the two lithium cations, perhaps by di-(isopropyl)amine.94... 

The different behaviour of, e. g., di-isopropyl amine and n-hexyl amine now becomes explicable. The sterically unhindered n-hexyl amine mainly functions as a Lewis base which adds to the Lewis acid (the NCA) and initiates the simple amine-propagated polymerisation. On the other hand, the sterically hindered di-iso-propyl amine is inefficient as a Lewis base but, being a more powerful Bronsted base than n-hexyl amine, it initiates a rapid polymerisation resulting from the proton abstraction and the "activation of the monomer. This is seen in Fig. 7 (see also p. 19). 

SFE/derivatization of several chlorinated acid pesticides (those listed in EPA method 515.1) have been performed using conditions similar to those used for the bacterial phospholipids. The derivatized products from the SFE procedure for several representative organics are shown in Figure 6. As would be expected using the TMPA/methanol reagent, the carboxylic acids form the methyl esters (2,4-D and dicamba) while the phenols form the methyl ethers (pentachlorophenol). Esters of the carboxylic acids (e.g., the di-isopropyl amine ester of 2,4-D) also form the methyl esters. For ethers, two derivatized products resulted since the ether linkage could be cleaved on either side of the oxygen and methylated as shown by acifluorfen. 

Di isopropyl amine was distilled from calcium hydride prior to use. 2-Methylpropanal was distilled prior to use. 

M n-Butyllithium (5.08 mmol) was added dropwise to di-isopropyl amine (2.5 mmol) dissolved in 190ml diethyl ether and the reaction stirred 1 hour at 0°C. Thereafter, the product from Step 1 (2.21 mmol) dissolved in 8 ml diethyl ether was added dropwise,... 

On the other hand, the reaction with diethyl amine or di-isopropyl amine under the same reaction conditions, affords diaminochloro-cyclopropenium perchlorate as the isolated product (Eqs. (7) and (8)). Since diphenylamine gives exclusively triaminocyclopropenium perchlorate, the bulkiness of the alkyl group of both the amines does not seem to be the reason. 

Difluoroethane Difluoromethane Di-isopropyl amine Di-isopropyl ether Di-isopropyl ketone... 

B. Furyl phoaphorodiohloridate. A 1-L flask, protected from moisture by a calcium chloride tube, is charged with 42 g (0.5 mol) of 2(5H)-furanone, 85 g (0.55 mol) of phosphoryl chloride and 100 mL of methylene chloride. A solution of 65 g (0.5 mol) of ethyl di isopropyl amine in 60 mL of methylene chloride 1s added dropwise during 4 hr at ambient temperature (Note 9). The resulting mixture is stirred overnight (12 hr), after which 6.5 g of the amine... 

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