Detergent workers

Similar studies showed a positive association between HLA alleles and development of IgE antibody. Sensitized platinum workers were DR3+ and DR6- while non-sensitized workers were DR3- and DR6+ [37], The linkage between HLA phenotype and development of IgE antibody was greatest among the low exposure group. A second study showed a relationship between HLA DR3 and IgE to inhaled anhydrides [38], A study among detergent workers showed a positive association between HLA-DR4+ and IgE antibody to the serine protease derived from Bacillus licheniformis [39],... 

Detergent workers disease Detergent Bacillus subtilis, enzymes... 

N. B. Godrej and co-workers. Proceedingsfirom "Alpha Olefins from Oleochemical Raw Materials," The Third World Detergent Confierence, Montreux, Switzerland, Sept. 1993. 

Every German worker washed his hands in the monopoly-suds of Farben detergents, on which every single soap factory in Ger-... 

The secretory vesicles have recently been discovered by Borregaard and co-workers (Sengelpv, Nielson Borregaard, 1992). These are very difficult to separate from the plasma membrane on density gradients. They possess latent alkaline phosphatase activity (i.e. subcellular fractions must be incubated with detergents such as Triton to release activity) and albumin, whilst the membranes contain CR1, CR3 and the fMet-Leu-Phe receptor. They are endocytic vesicles but can be rapidly translocated to the plasma membrane. 

Nicholson, P. J., Newman Taylor, A. J., Oliver, P., and Cathcart, M. (2001). Current best practice for the health surveillance of enzyme workers in the soap and detergent industry. Occup. Med. 51, 81-92. 

Despite these findings, mediation by enz3rmes present in dust remains an attractive hypothesis. Enzymes may exert their action in one of three ways 1) an allergic mechanism like that shown in workers exposed to subtills during detergent manufacture (22,23,24) where wheezing, shortness of breath, and/or rhinitis symptoms are shown to be mediated by specific IgE antibodies. 

No serious poisonings with decalin in humans have been reported. Inhalation of 100 ppm produces upper respiratory irritation. Contact with the liquid produced vesicular eczema, accompanied by intense itching, in a worker exposed to decalin and some detergents. ... 

The natural oils on a sea bird s feathers work to repel water, but they are miscible with the petroleum oils of an oil spill. The petroleum oils, therefore, readily adhere to and penetrate the feathers. The many air pockets within the feathers that normally serve to insulate the bird are lost, which is why the birds suffer hypothermia. Rescue workers are trained to remove these oils using liquid dishwashing detergent and warm water-... 

For some studies, washed lipid globules can be used as such. More commonly, it is necessary to dissociate membranes from globules by chemical or physical methods. Chemical methods normally involve direct extraction of constituents from the globules. Sodium dodecyl sulfate solutions have been used to recover membrane proteins from washed lipid globules for subsequent electrophoretic characterization (Kobylka and Carraway 1972 Mather and Keenan 1975). Other workers have used solutions of detergents such as deoxycholate (Hayashi and Smith 1965) and Triton X-100 (Patton 1982). With these deter-... 

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