Degree of concurrency

Results for the prediction of oral toxicity on rat are shown in Table 14. Bold values indicated that prediction is not reliable. Table includes also a limited number of experimental results provided by the model training dataset (some data are extracted from ChemID database). Globally, values show a high degree of concurrence. The only exceptions are the predictions of triclosan and methylisothia-zolinone toxicity for triclosan, prediction made by T.E.S.T. is more conservative than ToxSuite and experimental values while for methylisothiazolinone predicted values from T.E.S.T and ToxSuite are variable. 

If concurrency is employed, the documentation should specify how limits are enforced on the maximum allowable degree of concurrency and how accesses to shared data are synchronized in order to avoid (possibly undetected) run-time errors. 

By using these combinations we can have a high degree of concurrency control. Some experiences we have obtained are related to CORBA upcalls while waiting for requests to be completed. The behavior of the client is determined by the so called wait strategy. When an application acts as client and server, nested upcalls are possible and then we can have deadlock problems when the ORB steals direads of clients waiting for invocations. 

Each plant or laboratory should adopt definite rules and procedures for electrical iastahations and work. All iastahations should be ia accordance with the National Electrical Code (NEC) for the type of ha2ard, eg. Class I flammable gas or vapor Class II organic, metallic, or conductive dusts and Class III combustible fibers and the degree of process containment, eg. Division 1 open and Division 2 closed (67). Regardless of the flammabiUty of the materials ia the iastaHed operations, changes ia procedure involving use of such materials often occur, sometimes without concurrent alteration of the electrical iastaHation. 

A key success factor for reducing the costs and lead times for vehicle manufacturers, for example, is the degree of integration of the suppliers within the product development process. This is seen as a natural extension to concurrent engineering principles (Wyatt et al., 1998). For many years, in engineering companies, a substantial proportion of the finished product, typically two thirds, consists of components or subassemblies produced by suppliers (Noori and Radford, 1995). 

For many secondary sulfonates, nucleophilic substitution seems to be best explained by a concerted mechanism with a high degree of carbocation character at the transition state. This has been described as an exploded transition state. Both the breaking and forming bonds are relatively weak so that the carbon has a substantial positive charge. However, the carbocation per se has no lifetime because bond breaking and fonnadon occur concurrently."... 

Two possible reasons may be noted by which just the coordinatively insufficient ions of the low oxidation state are necessary to provide the catalytic activity in olefin polymerization. First, the formation of the transition metal-carbon bond in the case of one-component catalysts seems to be realized through the oxidative addition of olefin to the transition metal ion that should possess the ability for a concurrent increase of degree of oxidation and coordination number (177). Second, a strong enough interaction of the monomer with the propagation center resulting in monomer activation is possible by 7r-back-donation of electrons into the antibonding orbitals of olefin that may take place only with the participation of low-valency ions of the transition metal in the formation of intermediate 71-complexes. 

Most of the hterature reviewed concerning the health effects of endosulfan in humans described case reports of occupational exposure and accidental or intentional ingestion of endosulfan. The cases of occupational exposure to endosulfan concerned exposures of acute-to-intermediate durations, and the cases of oral exposure were exclusively acute-duration exposure situations. The predominant route of exposure in the occupational case reports is believed to be inhalation, but the possibility of some degree of dermal exposure cannot be ruled out. The information on human exposure is limited because the possibility of concurrent exposure to other pesticides or other toxic substances cannot be excluded. In addition, the precise duration and level of exposure to endosulfan generally cannot be quantified from the information presented in these reports. 

NSAIDs are classified as non-selective (they inhibit COX-1 and COX-2) or selective (they inhibit only COX-2) based on degree of cyclooxygenase inhibition. COX-2 inhibition is responsible for anti-inflammatory effects, while COX-1 inhibition contributes to increased GI and renal toxicity associated with non-selective agents. Since the antiplatelet effect of non-selective NSAIDs is reversible, concurrent use may reduce the... 

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