Dean effect

Curved Pipes and Coils For flow through curved pipe or coil, a secondary circiilation perpendicular to the main flow called the Dean effect occurs. This circulation increases the friction relative to straight pipe flow and stabilizes laminar flow, delaying the transition Reynolds number to about... 

Pressure drop in helical coils is dependent on whether the flow is laminar or turbulent. Typically flows are laminar at low fluid velocities and turbulent at high fluid velocities. In cuived pipes and coils a secondary circulation takes plac e called the double eddy or Dean Effect. VVliile this circulation increases the friction loss, it also tends to stabilize laminar flow, thus increasing the critical Reynolds number. 

DATTA-BARUA Natural Gas Measurement and Control DEAN Lange s Handbook of Chemistry, Fourteenth Edition DESHOTELS, ZIMMERMAN Cost-Effective Risk Assessment for Process Design... 

Azeotropic drying of organic substances is also effective, providing the material is relatively nonvolatile. A benzene or toluene solution of the compound is distilled (in a Dean-Stark trap, if available) until the distillate is free of water droplets. The remaining solution is essentially dry. 

No studies were located regarding gastrointestinal, hematological, musculoskeletal, or dermal effects in humans or animals after inhalation exposure to methyl parathion. Dean et al. (1984) reported that seven children exposed to methyl parathion by many routes exhibited pinpoint pupils, abdominal pain, and diarrhea. The respiratory, cardiovascular, hepatic, and renal effects reported by Fazekas (1971) that were found in humans acutely exposed to methyl parathion intoxication resulted from exposure by all three routes however, the results did not distinguish between the routes. 

Neurological effects related to cholinesterase depression occurred in seven children acutely exposed to methyl parathion by inhalation as well as orally and dermally (Dean et al. 1984). The children were admitted to a local hospital with signs and symptoms of lethargy, increased salivation, increased respiratory secretions, and miosis. Two of the children were in respiratory arrest. Two children died within several days of each other. All of the children had depressed plasma and erythrocyte cholinesterase levels (Table 3-2). These effects are similar to those occurring in methyl parathion intoxication by other routes (see Sections 3.2.2.4 and 3.2.3.4). Three adults exposed in the same incident had normal plasma (apart from one female) and red blood cell cholinesterase, and urinary levels of 4-nitrophenol (0.46-12.7 ppm) as high as some of the ill children. 

Neurological effects related to cholinesterase depression occurred in seven children acutely exposed to methyl parathion by inhalation as well as orally and dermally (Dean et al. 1984). See Section 3.2.1.4 for additional details. 

Often, absorption occurs by multiple routes in humans. Dean et al. (1984) reported deaths and toxic effects as well as lowered blood cholinesterase levels and excretion of urinary 4-nitrophenol in several children who were exposed by inhalation, oral, and possibly dermal routes after the spraying of methyl parathion in a house. In the same incident (Dean et al. 1984), absorption was indicated in adults who also excreted 4-nitrophenol in the urine, though at lower levels than some of the children, and in the absence of other evidence of methyl parathion exposure. In this study, the potential for age-related differences in absorption rates could not be assessed because exposure levels were not known and the children may have been more highly exposed than the adults. Health effects from multiple routes are discussed in detail in Section 3.2. 

Most of the toxic effects caused by methyl parathion resulted from exposure by multiple routes, especially for workers in sprayed fields or formulating facilities, or people in homes. Dean et al. (1984) reported deaths and toxic effects in several children as well as lowered blood cholinesterase levels and excretion of urinary 4-nitrophenol (adults showing no adverse effects also excreted 4-nitrophenol). 

Dean BJ. 1972. The mutagenic effects of organophosphorus pesticides on micro-organisms. Arch Toxicol 30 67-74. 

Other additional studies or pertinent information that lend sunnort to this MRL Methyl parathion affects the nervous system by inhibiting acetylcholinesterase activity. Cholinesterase inhibition and neurological effects have been observed in humans and animals, for all exposure routes and durations (for example. Dean et al. 1984 Desi et al. 1998 EPA 1978e Gupta et al. 1985 Nemec et al. 1968 Suba 1984). 

Behan, J. M. Dean, F. M. Johnstone, R. A. W. Photoelectron spectra of cyclic aromatic ethers the question of the Mills-Nixon effect. Tetrahedron 1976, 32, 167-171. 

Dean, R A., R. S. Dougall, and L. S. Tong, 1971, Effect of Vapor Injection on Critical Heat Flux in a Subcooled R-l 13 (Freon) Flow, Proc. Int. Symp. on Two-Phase Flow Systems, Haifa, Israel. (6) Deane, C. W., and W. M. Rohsenow, 1969, Mechanism and Behavior of Nucleate Boiling Heat Transfer to the Alkali Liquid Metals, USAEC Rep. DSR 76303-65, Massachusetts Institute of Technology, Cambridge, MA Also in 1970, Liquid Metal Heat Transfer and Fluid Dynamics J. C. Chen and A. A. Bishop, Eds., ASME Winter Annual Meeting, New York. (4)... 

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