Nonstructural data

Pharmaceutical companies are making significant investment to mine data, transfer old, nonstructured, often report-based data into central data warehouses for common access. The rapid change in IT infrastructure and technologies for data storage has created a very difficult environment where access to data can be cumbersome and requires enormous efforts and investment. 

This review will summarize and critically evaluate the crystallographic data for bacteriorhodopsin and its photointermediates. We will attempt to correlate the structural with the nonstructural data in order to explore the various and often contradictory mechanistic conclusions drawn. 

Nonstructural chemical data includes any textual, numeric, or binary data that is not directly a part of the chemical structure. It includes the following ... 

X-Ray photoelectron spectroscopy data showed an increase of about 20% in the Al/Si ratio as the outgassing temperature was increased from 773 to 1173 K, indicating that the surface concentration of A1 increased (169). Treat-ment with HCl to dissolve nonstructural aluminum produced a 15% decrease in the aluminum content of the sample calcined at 1173 K with respect to the 773 K sample. Subsequently, a small extent of dealumination occurred during the dehydroxylation at high temperature. It was suggested that aluminum from the lattice was extracted on calcination and resulted in an aluminalike species that stayed within the cavities of the zeolite. 

The data presented here were acquired using nonstructured polymer films with large-area grafted polymer brush layers. Note that light can quite easily be focused to a spot size on the order of micrometers or be directed to the sample using fiber optics, allowing for the acquisition of data from areas with micrometer dimensions and for characterization of structured samples with micrometer resolution. Furthermore,... 

Avoiding nonstructural or structural Mure can depend in part on the ability to predict performance of materials. When required designers have developed sophisticated computer methods for calculating stresses in complex structures using different materials. These computational methods have replaced the oversimplified models of materials behavior relied upon previously. The result is early comprehensive analysis of the effects of temperature, loading rate, environment, and material defects on structural reliability. This information is supported by stress-strain behavior data collected in actual materials evaluations. 

Diagnosis and management of CVD relies on a variety of medical data, such as ECG, ultrasound images, MRI images, CT images, biochemical exams, clinical profiles, and other data, such as patient history. The data that are mentioned above contain a wealth of information that is very useful for the physician but, due to their nonstructured format and the fact that the sources are heterogeneous, their retrieval is neither fast nor accurate. Therefore, semantic interoperability is important. Semantic interoperability can be broadly defined as the ability of one system to receive information from another system and reliably apply its... 

It is quite apparent now that not all the dimensions have the same importance, and that, owing to the correlations among the variables, the real" dimensionality of our data matrix is somehow lower than v. Therefore, it would be very valuable to have a technique capable of concentrating in a few variables, and therefore in a few dimensions, the bulk of our information. This is exactly what is performed by PCA it reduces the dimensionality of the data and extracts the most relevant part of the information, placing into the last dimensions the nonstructured information, i.e., the noise. According to these two characteristics, the information contained in very complex data matrices can be visualized in just one or a few plots. 

Westaway (1977) has proposed that three structural polypeptides, C, E, and M as well as five nonstructural polypeptides are separately initiated and terminated during translation, which would make the flavivirus mRNA unique since most other animal mRNAs studied to date have only a single translation initiation site, with a few exceptions (Kozak, 1981 Strauss and Strauss, 1983). On the other hand, Wengler et al. (1979) and Svitkin et al. (1981) reported that in an in vitro translation system only a single initiation site appeared to be used. The entire sequence of the flavivirus genome as well as amino acid sequence data for the polypeptides will be required to decide between these alternative translation strategies. 

The search request, as received from the user, consists of three basic types of search elements nonstructural data, exact structure data, and substructure data. The syntax parser classifies each element of the search request into one of the three... 

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