Cyproheptadine Alcohol

Although sedative antihistamines do not potentiate the effect of alcohol, they should be avoided in excess quantity. Overdose of astemizole can be treated with gastric lavage and supportive measures.86 Coadministration of astemizole and ter-fenadine with antiarrhythmics, antipsychotics, cisapride, and diuretics should be avoided. Chlorpheniramine maleate has been found to be incompatible with phe-nobarbitone sodium, kanamycin sulfate, and calcium chloride. Cyclizines have been used alone or with opioids in tablets or in injectable form for euphoric effects. Cyproheptadine has shown dependence in long-term use. Diphenhydramine is reported to be incompatible with amphotericin, cephalothin sodium, and hydrocortisone sodium succinate. Diphenhydramine and pheniramine maleate are sometimes used as drugs of abuse. Studies have shown that promethazine is adsorbed onto glass, plastic containers, and infusion systems.87... 

Cyproheptadine Hydrochloride. USP. Cyproheptadine hydrochloride. 4-(5//-dibcnzo- a.d -cyclohepten-.5-yli-dcnc)-l-methylpiperidinc hydrochloride scsquihydrate tl r-iactin), is slightly soluble in water and sparingly soluble in alcohol. 

Subsequently, Chan reported on twenty-four cases of overdose of a product containing valerian dry extract 75 mg, hyoscine hydrobromide 0.25 mg, and cyproheptadine hydrochloride 2 mg. Six patients developed vomiting, and fifteen underwent gastric lavage. Co-ingestants included alcohol (n = 10), cold products n = 3), hypnotics (n = 2), unknown drugs (n = 2), and gasoline (n = 1). Symptoms were mainly central nervous system depression and anticholin-... 

---