Cyanogen bromide chloride

Compare the dipole moments of cyanogen bromide (BrC=N) and cyanogen chloride (C1C=N) Which IS larger" Why" What does this tell you about the electronegativity of the CN group" ... 

Nitrile Synthesis. Cyanogen bromide [506-68-3] condenses with toluene in the presence of aluminum chloride to give -tolunittile (129). 

Cyanogens Cyanogens Hydrogen cyanide Cyanogen chloride Cyanogen bromide Cyanogen iodide Acetonitrile Acrylic nitrile... 

The pyrrolidine enamine of 2-tetralone (177) was converted to l-cyano-2-tetralone, which exists almost entirely in the enolic form (178), by reaction with cyanogen chloride (J23). Reaction of 177 with cyanogen bromide gave N-naphthylpyrrolidine (179), presumably via the unstable bromoenamine (180). The latter observation is in accord with the mode of reaction of the heterocyclic enamine (126) with cyanogen bromide, which resulted in the... 

Cyan-Mthert m. cyanic ester. -Mthyl, n. ethyl cyanide, -bad, n. cyanide bath. -baryum,n. barium cyanide, -benzol, n. cyanobenzene. -bromid, n. cyanogen bromide, -calcium, n. calcium cyanide, -chlorid, n. cyanogen chloride. -doppelsalZt n. double cyanide. 

Dibenz[b,/]azepinc-5-carbonitrile (14), an alternative intermediate for the synthesis of Car-bamazepine, is obtained (47%, as the hydrobromide) by stirring 5//-dibenz[b,/]azepine (5) with cyanogen bromide in chloroform solution at room temperature,203 or with cyanogen chloride in dimethylacetamide.204... 

Compared to polycarbonates, little work has so far been published on the synthesis of poly(iminocarbonates). The first attempted synthesis of a poly (iminocarbonate) was reported by Hedayatullah (44), who reacted aqueous solutions of various chlorinated dipheno-late sodium salts with cyanogen bromide dissolved in methylene chloride. Unfortunately, Hedayatullah only reported the melting points and elemental analyses of the obtained products which, according to Schminke (40), were oligomers with molecular weights below 5000. 

A number of amidines have anthelmintic activity. Bunamidine (25), indicated for treatment of human pinworm infestations, is prepared from a-naphthylhexyl-ether (23) by Friedel-Crafts type reaction with cyanogen bromide and aluminum chloride to give nitrile (24). This, then, is reacted with the magnesium bromide salt of di-n-propylamine leading to the naph-thamidine structure (25). -... 

In this series, too, replacement of the N-methyl by a group such as cyclopropylmethyl leads to a compound with reduced abuse potential by virtue of mixed agonist-antagonist action. To accomplish this, reduction of 24 followed by reaction with tertiary butylmagnesium chloride gives the tertiary carbinol 27. The N-methyl group is then removed by the classic von Braun procedure. Thus, reaction with cyanogen bromide leads to the N-cyano derivative (28) hydrolysis affords the secondary amine 29. (One of the more efficient demethylation procedures, such as reaction with ethyl chloroformate would presumably be used today.) Acylation with cyclopropylcarbonyl chloride then leads to the amide 30. Reduction with lithium aluminum hydride (31) followed by demethylation of the phenolic ether affords buprenorphine (32).9... 

Cyanogen bromide is moderately endothermic (AH°f (g) +50 kJ/mol, 0.47 kJ/g) and shows evidence of instability. The plastic cap of a bottle stored in a laboratory for several years on a high shelf, occasionally at 31°C, shattered and drove fragments into the shelf above [1]. This instability was confirmed, and a procedure outlined to obviate the use of the bromide in autoanalysis by generating cyanogen chloride on demand from Chloramine-T and potassium cyanide [2], A 50 wt% solution of the bromide in chloroform is a stable and convenient form for use [3], See Cyanogen chloride... 

See other catalytic impurity incidents See Ammonium chloride See Cyanogen bromide... 

Cyanogen bromide (CNBr) method, for covalent ligand immobilization, 6 396t Cyanogen chloride, 3 172 Cyanoguanidine, 3 164 Cyanohydrins, 27 229... 

Xie Y, Reckhow DA. 1993. A rapid and simple analytical method for cyanogen chloride and cyanogen bromide in drinking water. Water Res 27(3) 507-511. 

Calcium azide, 3936 f Carbon disulfide, 0560 Chlorine dioxide, 4042 Chloroacetylene, 0652 Chloryl perchlorate, 4104 Copper(I) azide, 4287 Cyanamide, 0404 Cyanoform, 1383 Cyanogen bromide, 0313 Cyanogen chloride, 0323 Cyanogen fluoride, 0323... 

CYANOGEN BROMIDE CYANOGEN CHLORIDE CYANOGEN FLUORIDE CARBON MONOXIDE CARBONYL SULFIDE CARBON OXYSELENIDE CARBON DIOXIDE CARBON DISULFIDE CARBON SELENOSULFIDE CYANOGEN... 

CARBONYL FLUORIDE UREA THIOUREA CYANOGEN BROMIDE CYANOGEN CHLORIDE... 

---