Manufacturing, custom

CCL Custom Manufacturing Inc. DanvUle, Dl. Personal Insect RepeUent spray 10.5... 

Give notice to terminate custom manufacturing agreement. ... 

Customers manufacturers Polymerizers Processors end users end users End users... 

Bio-Concept Laboratories Inc. is a comprehensive facility with infrastructure for supporting product development and delivery projects, which operates on a customer contract basis. Chemical, biochemical, and microbiological are addressed in a complete aseptic fill suite for the customized manufacture of sterile clinical and toxicology products. 

Chemi Proprietary diphosphine ligands, process R D, custom manufacturing. Some pilot and bench scale processes. 

Fine-chemical/custom manufacturing (CM) companies account for the largest share of the industry, followed by contract research organizations (CROs) and laboratory chemical suppliers. 

Fine-chemical/custom manufacturing companies (discussed in Section 2.1) are active in process scaleup, pilot plant (trial) production, and industrial-scale exclusive and nonexclusive manufacture contract research organizations are discussed in Section 2.2, and laboratory chemical suppliers are discussed in Section 2.3. 

Fine chemicals are produced either in-house by pharmaceutical or other specialty chemical companies for their captive needs, or as sales products by fine-chemical companies. The latter account for about one-third of the total production value of 75 billion, and obviously for the totality of the trading volume (see Table 9.2). In business transactions, custom manufacturing (CM) prevails over straight trading of standard products. 

Most of today s best-known hne-chemical companies, such as Cambrex, Clariant, Degussa, Dowpharma, DSM, and Rhodia (see Table 2.2), are subject to the abovementioned characteristics. Customers prefer to do business with midsize companies, because communications are easier (they typically deal directly with the decisionmaker)—and they can better leverage their purchasing power. Lonza s custom manufacturing business, apart from biotech, is still mainly concentrated on the original Visp, Switzerland site in terms of production and R D, and therefore has conserved a number of advantages that are typical of midsize companies. 

Sigma Aldrich, USA. The company had sales of 1.7 billion in 2005 and serves 60,000 accounts representing over one million individual customers. Apart from offering 100,000 small and big molecules, including cell culture media, it has also 30,000 items of laboratory equipment available. Under the name SAFC Pharma, a 65 million PFC (including HPAI) custom manufacturing business is operated. 

Analytical Development. The increasingly complex molecules require a permanent development of new, sophisticated analytical methods and, if required, their validation. In order to fulfill this demanding task, a well-equipped state-of-the-art analytical laboratory has to be accessible. In custom manufacturing projects, a close cooperation between the analytical departments of the customer and the supplier is essential for a successful completion of a project. 

In custom manufacturing, a typical project starts with the acceptance of the product idea, which comes mainly from business development, by the new product committee, followed by the preparation of a laboratory process, and ends with the successful completion of demonstration runs on industrial scale and the signature of a multiyear supply contract, respectively. The technical... 

The average return on net operating assets (RONOA) of the sample was 9%. The last two figures exemplify the capital intensity of custom manufacturing (CM)-biased fine-chemical companies. In order to achieve a good return of capital employed, a healthy margin is mandatory. A more standard... 

A manufacturing company can basically be organized according to assets, geographic regions, or businesses. More than in other industries, the destiny of the fine-chemical/custom manufacture industry depends on the individual... 

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