Cushing

Cushing s disease Cushing s syndrome Cushioning applications... 

Antagonists of glucocoiticoid and mineral ocorticoid activity have found iacieased use clinically ia the treatment of hypertension, Cushing s disease, and heightened iatraocular pressure. 

Other Potassium and Sodium Disorders. Potassium and/or sodium deficiency can lead to muscle weakness and sodium deficiency to nausea. Hyperkalemia resulting in cardiac arrest is possible from 18 g/d of potassium combined with inadequate kidney function. Faulty utilisation of K" and/or Na" can lead to Addison s or Cushing s disease. 

Davenport, D., Wootton, T. M., and Cushing, J. E. (1952). The biology of the Sierra luminous millipede, Luminodesmus sequoiae Loomis and Davenport. Biol. Bull. 102 100-110. 

Cushing s syndrome a disease caused by the overproduction of endogenous glucocorticoids... 

Carter JL, Resh VH (2005) Pacific coast rivers of the coterminous United States. In Benke AC, Cushing CE (eds) Rivers of North America. Elsevier Inc, San Diego, pp 541-590... 

Attree RW, Cabell MJ, Cushing RL, Pieroni JJ (1962) A calorimetric determination of the half-life of thorium-230 and a consequent revision to its neutron capture cross section. Can J Phys 40 194-201 Bateman H (1910) Solution of a system of differential equations occurring in the theory of radioactive transformations. Proc Cambridge Phil Soc 15 423-427 Beattie PD (1993) The generation of uranium series disequilibria by partial melting of spinel peridotite ... 

Lemeille F, Cushing M, Carbon D, Grellet B, Bitterli T, Flehoc C (1999) Co-seismic raptnres and deformations recorded by speleothems in the epicentral zone of the Basel earthqnake. Geodinam Acta 12 179-191... 

Haigh G., Cushing B.S. and Bronson F. (1988). A novel post-copulatory block to reproduction in White-footed mice. Biol Reprod 38, 623-626. 

Example, Bartter s or Gitelman s syndrome, Cushing s syndrome, hyperaldosteronism (1° or 2°), and Liddle s syndrome... 

Cushing s syndrome and other glucocorticoid excess states... 

Alzheimer s disease Cerebral infarction Cerebral tumors Closed head injury Cushing s syndrome Hemodialysis Hepatic encephalopathy Huntington s disease Hyperthyroidism Ictal or post-ictal mania Multiple sclerosis Neurosyphilis... 

Recognize the clinical presentation of Cushing s syndrome and the physiologic consequences of cortisol excess. 

Recommend strategies to prevent the development of Cushing s syndrome associated with exogenous glucocorticoid administration. 

Describe the pharmacologic and nonpharmacologic management of patients with Cushing s... 

Recommend therapy monitoring parameters for patients with Cushing s syndrome. 

Patients with Cushing s syndrome owing to endogenous or exogenous glucocorticoid excess typically present with similar clinical manifestations. 

Surgical resection is considered the treatment of choice for Cushing s syndrome from endogenous causes if the tumor can be localized and if there are no contraindications. 

Monitor for adverse reactions from hydrocortisone administration. Glucocorticoid therapy at physiologic replacement doses should not lead to the development of Cushing s syndrome. However, careful monitoring should still be performed. Use the smallest effective dose. 

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