Cre

Biosynthesis. CRE is derived from a precursor of 196 amino acids (84,85). This gene contains one copy of CRE, which is flanked by double basic amino acids. The amino acid sequence of the CRE precursor suggests that it may arise from proteins related to POMC and neurophysins (31). The CRE precursor contains a cAMP responsive element which aHows stimulation of mRNA synthesis when intraceHular levels of cAMP are increased (86). 

Such findings suggest that specific CRE antagonists maybe valuable tools in the treatment of depression. 

Because of the toxicity of lead, special care must be taken when working with lead ahoys. Lead and its inorganic compounds are neurotoxias which may produce peripheral neuropathy. Eor an overview of the effects of lead exposure, see Occupational Exposure to Lead, Appendix A (29 CRE 1910.1025) (see... 

Pig. 3. Representation of promoter sites on the pro-enkephalin gene. The numbers represent the distance in nucleotides from the pro-enkephalin initiation codon the arrow indicates the direction of transcription. The TATA promoter box occurs immediately before the pro-enkephalin initiation site the AP-2 site, which binds immediate-early gene products, is 70 nucleotides upstream, and the CRE site, which binds a regulatory protein involved in cAMP induction of mRNA synthesis, is 107 nucleotides upstream from the initiation codon. The expanded section shows that the CRE site actually consists of two elements, ENKCRE-1 and ENKCRE-2, which separately confer cAMP sensitivity to pro-enkephalin mRNA synthesis. 

There is Httie recent information on the Exxon and BASE processes (85—87). The CRE, Exxon, and BASE processes use sulfuric acid as the extraction medium. The BASE process is the dominant process in Europe. It uses the dHutest acid of any commercial process. This permits selective reaction even in the presence of butadiene. The BASE process uses vapor—Hquid extraction unlike the Exxon and CRE processes which are of the Hquid—Hquid type. 

CDU in pure form is a white powder. It is made slowly available to the soil solution by nature of its limited solubihty in water. Once in the soil solution, nitrogen from CDU is made available to the plant through a combination of hydrolysis and microbial decomposition. As with any CRE which is dependent on microbial action, the mineralization of CDU is temperature dependent. Product particle size has a significant effect on CDU nitrogen release rate. Smaller particles mineralize more rapidly because of the larger surface contact with the soil solution and the microbial environment. The rate of nitrogen release is also affected by pH because CDU degrades more rapidly in acidic soils. 

Released wirh practically no velocity. into quiet dir Kvaporarion from ranks, degreasing, cre. 0.25-0,5 )... 

An explosion at tlie Nypro Ltd. caprolactam factory at Flixborough, England, on June 1, 1974, was one of the most serious in tlie liistory of tlie chemical industry and tlie most serious in tlie liistory of the United Kingdom. Of tliose working on tlie site, 28 w cre killed and 36 others injured. Outside tlie plant, 53 people were... 

Common Name o-Cresyl glycerol ether, glyceryl O-tOlyl ether, cresoxypropanediol, cres-oxydlol... 

In the 1990s, Japan s smaller insular and peninsular neighbors, Taiwan and South Korea, began to cre-... 

Processes involving less corrosive organic acid such as carbolic, cre-sylic, salicylic and many others, are satisfactorily catered for by the nonmolybdenum steels. This also applies to the less corrosive inorganic acids such as boric, nitrous, and carbonic and silicic. 

CREB stands for cyclic-AMP response element (CRE) binding protein and is a transcription factor. When phosphorylated by cyclic AMP- and cyclic GMP-dependent Protein Kinases or other protein kinases it binds to gene promoters that contain a specific binding site. After binding, the respective transcription activity is modulated. 

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