Cosmeceutical

Cl. Bleve, M., Ciurlia, L., and Rescio, L., Supercritical carbon dioxide extracts from red fruits a natural cosmeceutical application, Nutra. Cos., 4, 23, 2005. 

Most of the water on Earth s surfece is in the ocean relatively little is present in the atmosphere or on land. Because of its chemical and physical properties, this water has had a great influence on the continuing biogeochemical evolution of our planet. Most notably, water is an excellent solvent. As such, the oceans contain at least a little bit of almost every substance present on this planet. Reaction probability is enhanced if the reactants are in dissolved fitrm as compared with their gaseous or solid phases. Many of the chemical changes that occur in seawater and the sediments are mediated by marine organisms. In some cases, marine organisms have developed unique biosynthetic pathways to help them survive the environmental conditions fitimd only in the oceans. Some of their metabolic products have proven useful to humans as pharmaceuticals, nutraceuticals, food additives, and cosmeceuticals. 

On the other hand, squalane is a saturated derivative of squalene which also was identified in human sebum. Its inert properties and suggested low toxicity compared to its analog squalene gained attraction from researchers, especially in the area of cosmetics (Allison, 1999). Proved emollient and moisturizing properties of squalane paved its way into protective nutraceutical and cosmeceutical area along its unsaturated relative, squalene. 

Further, squalane also exists in sebum composition. Additionally, due to its unique properties and more stable nature as industrial product than squalene, squalane is highly preferable in cosmeceutical and nutraceutical... 

Owing to the immense diversity of animals and microbes in the marine environments, and their almost untouched capacity to produce natural products, the importance for marine pharmaceutical and nutra-ceutical industries was realized on a broad basis by the scientific communities recently. This has strengthened worldwide research activities on the exploration of bioactive compounds from marine organisms for pharmaceutical use, as well as the development of other valuable products, such as enzymes, nutraceuticals, and cosmeceuticals. 

Chapter 6. Cosmeceuticals Accutane , Tazorac , Rogaine , and Propecia ... 

Cosmeceuticals are substances that are applied to skin or hair but do not modify its structure and function. One aspect that differentiates cosmeceuticals from cosmetics is that most, if not all, of them originate from bona fide medicinal chemistry programs. In this chapter, four representative cosmeceuticals are discussed isotretinoin (1) and tazarotene (2) for acne and minoxidil (3) and finasteride (4) for hair growth, respectively. Ironically, in spite of their market successes, neither minoxidil nor... 

The ability to encapsulate active ingredients in emulsions, foams, and suspensions, is leading manufacturers to make personal care products that are also pharmaceutical, termed cosmeceuticals. Examples creams with anti-wrinkle properties, lotions with anti-baldness effects, and sunscreens that treat skin damage (see also Chapter 15). 

Beyond facial creams, facial masks are usually concentrated partide suspensions, and are used to treat and refresh facial skin. The particles are usually either kaoli-nite, Fuller s earth, or illite ( green clay ) or other days. The particles are intended to act as exfoliants and also to adsorb oils from the skin. Other additives span a wide range of materials, including essential oils, vitamins, fruits and vegetables, scents, and pharmaceutical (cosmeceutical) additives, such as salicylic acid when added to treat mild acne. Body clays are like facial masks except that a higher concentration of clay is used in the suspension. 

Moisturizers form a prominent part of the skin healthcare market, which currently estimated at US 8 billion. It is a growing market.39,40 The effect on the economy is however not limited to producers of cosmetics or cosmeceuticals. Moisturizers regularly advertised and as such probably give substantial revenue for all media companies. These creams and lotions therefore form a valuable consumer good which is produced and marketed on an industrial scale, and is subject to the same mechanisms as other consumer goods. 

Chapter 6. Cosmeceuticals Accutane8, Tazorac8, Rogaine8, and Propeda ... 

Cosmeceuticals, Drugs vs. Cosmetics Eisner, P. Maibach, H. I., Eds. Marcel Dekker New York, 2000. 

Lipid nutritional supplements have been in use before the term nutraceutical was coined. Products such as fish oils, shark cartilage, shark liver oil, and vitamins have been in the market since the beginning of the twentieth century. Some of the health claims of these products lacked strict scientific documentation in the past, and their curative properties were mostly anecdotal. However, today there is a better understanding of the biological properties of lipids and their application has extended to combined pharmaceutical and cosmetic fields such as disease prevention and treatment, excipients and coadjuvants, frawi-dermal carriers, and skin emolliency agents. This has led to the development of bioactive cosmetic and pharmaceutical products whose name has recently been coined as cosmeceuticals. 

Other Applications Biotechnology, Nutraceutic, Cosmeceutic, and Biopharmaceutic.616... 

This new process would have two advantages, the production of a phospholipid-enriched fraction, which could be used in cosmeceuticals and nutraceuticals and a purihed (demineralized and delipided) and more valuable protein fraction after concentration of the whey. EDBM process could be a part of the first step of WPC treatment for the valorization of the whey in the form of lipid fractions of different nature. In comparison with the chemical acidification, EDBM process has the... 

Medicinal products classified as cosmeceuticals may now be registered in Poland under a one-step procedure. Cosmeceuticals are cosmetics with properties that correct or modify physiological processes and treat or prevent disease. As medicinal products, they are considered to be supplemental to essential therapy and are mostly topically-applied products for dermatological conditions. Under the new registration procedure, documentation requirements are the same as for applications to register human medicines, namely pharmacological, toxicological, clinical and pharmaceutical/chemical documentation. 

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