Comus kousa

Ishimaru, K., N. Tanaka, T. Kamiya, T. Sato, and K. Shimomura. 1998. Comus kousa (dogwood) in vitro culture, and the production of tannins and other phenolic compounds. In Bajaj, Y. P. S. (ed.). Biotechnology in Agriculture and Forestry 41. Medicinal and Aromatic Plants X. Springer-Verlag. New York. p. 113-131. 

Delphinidin-3-O-glueoside and delphinidin-3-O-rutinoside isolated from Comus kousa fruits were evaluated for their inhibitory activities on tumor cell proliferation, lipid peroxidation and cyelooxygenase enzymes (COX), showing potent effects [Vareed et al., 2006]. 

A new lignan glycoside was also identified in the methanol extract of fruits of Comus kousa L. comuskoside A [Lee et al., 2008a], This compound is a xylopyranoside of dihydrodehydroconiferyl alcohol and was isolated for the first time from a natural source in these fruits. 

Figure 6, Lignans isolated from Comus kousa L. fruits.

Ursolic aldehyde isolated from Comus kousa fruits was reported to possess an inhibitory activity against phosphatase of regenerating liver-3 (PRL-3), a key contributing factor in the development of metastatie properties of tumor cells [Lee et al., 2010a],... 

Vareed, SK, Schutzki, RE, Nair, MG. Lipid peroxidation, cyclooxigenase enzyme and tumor cell proliferation inhibitory eompounds in Comus kousa fruits. Phytomedicine, 2007, 14, 706-709... 

Comus alba L. C. kousa Hance C. macrophylla Wallich Si Zhao Hua Jian Zi Mu (Dogwood) (bark, shoot, leaf) Quercitol, kaempferol, dihydroxyglutamic acid, phenethylamine.48 Astringent, antimalarial, treat arthritis, backache, diabetes, hepatitis, malaria, metrorrhagia, cancer. 

Celosia argentea, C. cristata, C. margariacea, Ficus carica, Hippophae rhamnoides Comus alba, C. kousa, C. macmphylla, Euphorbia hirta, Fagopyrum esculentum, F. sagittatum, Viscum album, V. coloratum... 

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