Computer Aided Operation

Rekalitis, G. V, and H. D. Spriggs. Proceedings of the First Inteinational Conference on Foundations of Computer-Aided Operations. Elsevier Science Publishers, Inc., New York (1987). 

Rippin, D. W. T, J. C. Hale, and J. F. Davis (ed.). Proceedings of the Second International Conference on Foundations of Computer-Aided Operations. CACHE Corporation, Austin, TX (1994). 

Pantelides, C.C. (1994) Unified frameworks for optimal process planning and scheduling, in Proceeding of the Second Conference on Foundations of Computer-Aided Operations, CAChE Publications, p. 253. 

Scientific Design Company, Inc. Ethylene oxide Ethylene or ethanol and oxygen Improved catalyst and computer-aided operations yield high-quality product 95 1998... 

J.Savkovic-Stevanovic, T.Mosorinac, S.Krstic, R.Beric, 2007, Computer aided operation and design of the cationic surfactants production- Chapter, Chemical Engineering-24, Escape 17,Eds. V.Plesu and P.S.Agachi, Elsevier Science,p.l95-200. 

In Computer Aided Operation we can mention the real time monitoring of material and energy balance, managed nowadays by means of data reconciliation programs. The plant operation can be adapted and optimised in real time by means of computerised tools based on dynamic flowsheeting. Other advanced applications are simulators for safety studies and operator training. 

This paper describes the development of a novel system for improving the quality of information provided by manual ultrasonic examination of welds, while retaining the flexibility of the human operator to apply the techniques to components of a wide range of geometries and dimensions. The system, known as CamuS (Computer Aided Manual UltraSonics) provides assistance to the manual operator in two separate areas ... 

Industrial scale polymer forming operations are usually based on the combination of various types of individual processes. Therefore in the computer-aided design of these operations a section-by-section approach can be adopted, in which each section of a larger process is modelled separately. An important requirement in this approach is the imposition of realistic boundary conditions at the limits of the sub-sections of a complicated process. The division of a complex operation into simpler sections should therefore be based on a systematic procedure that can provide the necessary boundary conditions at the limits of its sub-processes. A rational method for the identification of the subprocesses of common types of polymer forming operations is described by Tadmor and Gogos (1979). 

The use of the computer in the design of chemical processes requires a framework for depiction and computation completely different from that of traditional CAD/CAM appHcations. Eor this reason, most practitioners use computer-aided process design to designate those approaches that are used to model the performance of individual unit operations, to compute heat and material balances, and to perform thermodynamic and transport analyses. Typical process simulators have, at their core, techniques for the management of massive arrays of data, computational engines to solve sparse matrices, and unit-operation-specific computational subroutines. 

Eault tree analysis (ETA) is a widely used computer-aided tool for plant and process safety analysis (69). One of the primary strengths of the method is the systematic, logical development of the many contributing factors that might result ia an accident. This type of analysis requires that the analyst have a complete understanding of the system and plant operations and the various equipment failure modes. 

J. P. Boston, H. 1. Britt, S. Jkaphongphan, and V. B. Shah, "An Advanced System for the Simulation of Batch Distillation Operations," in Foundations of Computer-Aided Chemical Process Design, Vol. 2, American Institute of Chemical Engineers, New York, 1981. 

Dove, M.J., Burns, R.S. and Evison, J.L. (1986) The use of Kalman Filters in Navigation Systems - Current Status and Future Possibilities. In Proc. of the Int. Conf. on Computer Aided Design, Manf. and Operation in the Marine and Offshore Industries, Keramidas, G.A. and Murthy, T.K.S. (eds.), Springer-Verlag, Washington, DC, pp. 361-374. 

Goldberg, D.E. (1983) Computer-aided gas pipeline operation using genetic algorithms and rule learning (Doctoral dissertation. University of Michigan). Dissertation Abstracts International, 44(10), p. 3174B (University Microfilms No. 8402282). 

Computer-Aided Management of Emergency Operations, Version 1.02... 

Willie, R. R., 1978. Computer Aided Fault Tree Analysis," Operations Research Center, of Ca ifornia Berkeley. 

Goodstein, L. P. (1982). "Computer-Based Operating Aids." Report NKA/LIT— 3. 

The purification of value-added pharmaceuticals in the past required multiple chromatographic steps for batch purification processes. The design and optimization of these processes were often cumbersome and the operations were fundamentally complex. Individual batch processes requires optimization between chromatographic efficiency and enantioselectivity, which results in major economic ramifications. An additional problem was the extremely short time for development of the purification process. Commercial constraints demand that the time interval between non-optimized laboratory bench purification and the first process-scale production for clinical trials are kept to a minimum. Therefore, rapid process design and optimization methods based on computer aided simulation of an SMB process will assist at this stage. 

Using computer-aided numerical calculations, one can readily simulate and identify critical parameters for process validation. Thus, one can evaluate the robustness of the process during its design. To ensure performance, optimization of the process and evaluation of critical parameters can be determined before actual operating conditions. 

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