Compositae parthenium

Tanacetum parthenium (L.) Schultz Bip. is the official Latin name for the member of the Compositae family which is more commonly referred to as feverfew [6]. The plant had previously been classified as Chrysanthemum parthenium (L.) Bernh., so the latter name is strictly speaking no longer correct. Other old classifications for feverfew are Leucanthemum parthenium (L.) Gren. Godron or Pyrethrum parthenium (L.) Sm. 

In 1959-61, a Czech group [8,9] reported the isolation of a new sesquiterpene lactone from Chrysanthemum (Tanacetum) parthenium as part of a study of the sesquiterpene lactones of the Compositae family. They named it parthenolide. The initial structure for parthenolide was later revised [10,11] and the accepted structure for parthenolide today is represented by structure (1). Parthenolide is a germacranolide-type sesquiterpene lactone. The crystal structure for parthenolide has also been reported [12]. Extractions of C. (T.) parthenium grown in Mexico, known locally as santamaria, did not yield parthenolide [13], but a closely related compound was isolated and named santamarine (3). This suggests that regional variations in the chemical constituents may occur. 

More than 11,000 Sesquiterpenes have been isolated from natural sources [3]. Feverfew (Tanacetum parthenium (L.) Sch. Bip.,. Compositae) is a common herb utilized for fever, arthritis and migraine. The leaves of feverfew contain large amounts of sesquiterpene lactones. The chloroform extracts of fresh leaves and a commercial leaf product show dose-dependent inhibiting the production of throboxane B2 (TXB2) and leukotriene B4 (LTB4) in rat and human leukocytes. Sesquiterpene lactones isolated from the leaves of feverfew, such as parthenolide and tanaparthin-a-peroxide, demonstrate potent dual inhibitions of COX and LOX pathways with IC50 for COX at 6 17 pg/ml, and for LOX at 12 17 pg/ml, respectively [135],... 

Hausen, B.M., and P.E. Osmundsen. 1983. Contact allergy to parthenolide in Tanacetum parthenium (L.) Schulz-Bip. (feverfew, Asteraceae) and cross-reactions to related sesquiterpene lactone containing Compositae sjjecies. Acta Derm. Venereal. 63(4) 308-314. 

Burry JN (1980) Compositae dermatitis in South Australia 103. contact dermatitis from Chrysanthemum parthenium. Contact Dermatitis 6 445... 

Nandakishore T, Pasricha JS (1994) Pattern of crosssensitivity between 4 Compositae plants, Parthenium hysterophorus, Xanthium strumarium, Helianthus annuus and Chrysanthemum coronarium, in Indian patients. Contact Dermatitis 30 162-167... 

Taxonomy Cycloartane Triterpenoids Parthenium lozanianum Bartlett (Compositae) [1]. Colorless oil. 

Taxonomy Cycloartane Tiiterpenoids Parthenium argentatum Gray (Compositae) [1,2], CAS Registry Number 31324-30-8. 

The serious threat of disease to the viability of the industry has provided the opportunity for some countries to search for alternative sources of rubber latex from other plants. Guayule (Parthenium argentatum Gray) and Taraxacum koksaghyz (TKS) are plants in the Compositae family found in the temperate... 

Source Tanacetumparthenium (L.) Schulz. Bip. (syn. Chrysanthemum parthenium (L.) Bemh., Leucanthemum parthenium (L.) Gren. et Godron, and Pyrethrum parthenium L. Sm.) (Family Compositae or Asteraceae). 

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