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Complex functions hyperbolic

The operational model, as presented, shows dose-response curves with slopes of unity. This pertains specifically only to stimulus-response cascades where there is no cooperativity and the relationship between stimulus ([AR] complex) and overall response is controlled by a hyperbolic function with slope = 1. In practice, it is known that there are experimental dose-response curves with slopes that are not equal to unity and there is no a priori reason for there not to be cooperativity in the stimulus-response process. To accommodate the fitting of real data (with slopes not equal to unity) and the occurrence of stimulus-response cooperativity, a form of the operational model equation can be used with a variable slope (see Section 3.13.4) ... [Pg.47]

A plot of the initial reaction rate, v, as a function of the substrate concentration [S], shows a hyperbolic relationship (Figure 4). As the [S] becomes very large and the enzyme is saturated with the substrate, the reaction rate will not increase indefinitely but, for a fixed amount of [E], it reaches a plateau at a limiting value named the maximal velocity (vmax). This behavior can be explained using the equilibrium model of Michaelis-Menten (1913) or the steady-state model of Briggs and Haldane (1926). The first one is based on the assumption that the rate of breakdown of the ES complex to yield the product is much slower that the dissociation of ES. This means that k2 tj. [Pg.335]

In the three-branch horseshoe, the periodic oibit 0 is hyperbolic with reflection and has a Maslov index equal to no = 3 while the off-diagonal orbits 1 and 2 are hyperbolic without reflection with the Maslov index n = 2 [10]. Fitting of numerical actions, stability eigenvalues, and rotation numbers to polynomial functions in E can then be used to reproduce the analytical dependence on E. The resonance spectrum is obtained in terms of the zeros of (4.16) in the complex energy surface. [Pg.559]

The time courses of the effect and of the concentration in plasma are not identical, because the concentration-effect relationship is complex (e.g., with a threshold phenomenon) and often obeys a hyperbolic function (B cf. p.54). This means that the time course of the effect exhibits dose dependence also in the presence of dose-linear kinetics (C). [Pg.68]

Equations (1.80) and (1.81) provide relationships between complex variables and trigonometric functions. These can be manipulated to find relationships with hyperbolic function. Some important definitions and identities are presented in Table 1.6. ... [Pg.20]

The neurons weight all inputs and provide an output via the activation function. The complexity of the neural networks used will be determined by the number of nodes in the hidden layer (2,3,5 or 7). The activation applied in this application is a hyperbolic tangent function. In mathematical terms, the output of neuron j is defined by n With yj output of neuron j... [Pg.58]

The operational model, as presented, shows dose-response curves with slopes of unity. This pertains specifically only to stimulus-response cascades where there is no cooperativity and the relationship between stimulus ([AR] complex) and overall response is controlled by a hyperbolic function with slope = 1. In practice, it is known that there... [Pg.49]

Properties of Wave Functions in the Continuous Range,—For hyperbolic states the parameter I is imaginary as well as a l = IK, a = i [ a, A and a being real and positive). The question arises, therefore, whether the function x( ) is complex. It was shown (loc. cit.) that our series (1) is a limiting case of the hypergeometric series... [Pg.3]

With limited amount of Ab, the unlabeled antigen (analyte) competes with the labeled antigen Ag for limited binding sites. Bound fraction (AgAb) is separated from free (Ab), and the signal [Ag Ab] complex (the Ab fraction not occupied by the analyte) is measured. The amount of analyte is inversely proportional to the bound [Ag Ab] complex in a hyperbolic function as in Fig. 1. Methods for transforming or linearizing these functions are presented in the section on data reduction (Sec. V). [Pg.242]

The complex rate constant in eq 15 is a rectangular hyperbolic function. It is exactly equal to k) at infinite dilution (the low-[M ] limit) and asymptotically approaches kMi as [M1 increases to large values. ... [Pg.111]

In this chapter we have introduced symbolic mathematics, which involves the manipulation of symbols instead of performing numerical operations. We have presented the algebraic tools needed to manipulate expressions containing real scalar variables, real vector variables, and complex scalar variables. We have also introduced ordinary and hyperbolic trigonometric functions, exponentials, and logarithms. A brief introduction to the techniques of problem solving was included. [Pg.54]

The parameter Ka,s is the dissociation constant for the complex of enzyme a and the effector T or F, labeled s, while ra,s is the ratio of the catalytic rate constants for the enzyme with and without effector bound, respectively. This general form models both activators and inhibitors of the enzyme, depending on whether r is greater than or less than 1. The response described is hyperbolic, with the half-maximum effect exerted when e = K, and saturating at the maximum effect r for very high effector concentrations. The cumulative multiplication of modifying factors reflects the assumption that all effectors function at different sites on the enzyme and that the sites do not communicate. [Pg.108]

In equation (2.126) is density of the diffuse layer electric charge, a x) is volume density of the electric charge in the diffuse layer at the distance X. Through quite complex modifications, using hyperbolic function (sh), David K. Grahame in 1947 derived the equation for solutions of symmetric univalent salts (NaCl type)... [Pg.158]

Hyperbolic functions are copycats of the corresponding trigonometric functions, in which the complex exponentials in Eqs. (4.51) and (4.52) are replaced by real exponential functions. The hyperbolic sine and hyperbolic cosine are defined, respectively, by... [Pg.70]

We have considered only one function of an enzyme, namely, catalysis. An equally important function is to regulate metabolic fluxes. The kinetic behavior of regulatory enzymes can be quite complex the initial velocities are often not hyperbolic functions of substrate concentrations, and the binding of nonsubstrate metabolites can have profound kinetic effects. This fascinating subject is beyond the scope of this book, but many comprehensive reviews are available [31-34]. [Pg.243]

Although the patent citation hyperbolic tree has been applied by Thomson Innovation of the Thomson Reuters, the system is limited in the second level of the patent citations and patent references, and all the related patents are listed out at a time. The users receive the data passively and could not rapidly and selectively browse and look over the deeper level patents based on their own demands. The similar functions can be achieved through some alternative ways, but the operation complexity and system interaction time increase significantly. [Pg.217]

Of course, the hyperbolic functions will be replaced by the appropriate sinusoidal functions when 65 and/or 6n is complex. Thus, the theory in this form is capable of representing a wide range of reorientational behavior. One sees that the time dependence of is affected by the.presence of orientational... [Pg.134]


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