Cognitive event-related potentials

P300, one of the cognitive event-related potentials of the cerebral cortex may serve as a marker for measuring the course of Alzheimer s disease during treatment with donepezil. There was reduced P300 latency associated with parallel improvement of ADAS-J Cog scores after administration of donepezil 5 mg/kg in 13 patients with Alzheimer s disease (8 women and 5 men, aged 70-88 year) (90). 

Lai CL, Hsu CY, Liou LM, Hsieh HY, Hsieh YH, 2722. Liu CK (2011) Effect of cholesterol and CYP46 polymorphism on cognitive event-related potentials. Psychophysiology 48 1572-1577... 

Araki, S. (1992). Auditory event-related potential (P300) in relation to peripheral nerve conduction in workers exposed to lead, zinc, and copper Effects of lead on cognitive function and central nervous system. Amer. J. bid. M (Ed.), 21(4) 39-547. 

A few studies have been performed with event-related potentials (ERP) to examine the cognitive effects of THC. In subjects viewing emotionally valenced words (neutral, negative, or positive), THC produced a behavioral decrease in recognition rate (Leweke et al. 1998). The ERPs showed the typical difference between old and new words (enhanced positivity for old words beginning 250 milliseconds poststimulus), and THC enhanced the positivity in response to old words. This counterintuitive dissociation between ERPs and behavioral indices was interpreted as a reflection of implicit memory processes underlying the ERP effect. 

Semlitsch HV, Anderer P, Saletu B, Binder GA, Decker KA. (1995). Cognitive psychophysiology in nootropic drug research effects of Ginkgo biloba on event-related potentials (P300) in age-associated memory impairment. Pharmacopsychiatry. 28(4) 134-42. 

Pooviboonsuk, P., Dalton, J.A., Curran, H.V., Lader, MJL. The effects of smgle doses of lorazepam on event-related potentials and cognitive function. Hum. Psychopharmacol. II, 241-252, 1996. 

Bodis-WoUner I, Borod JC, Cicero B, Haywood CS, Raskin S, MyUn L, SUwinski M, Falk A, Yahr MD (1995) Modality dependent changes in event related potentials correlate with spe-ciflc cognitive function in non-demented patients with Parkinson s disease. J Neural Trans 9 197-209... 

Porjesz, B., 8c Begiciter, H. (1995). Event-related potentials and cognitive function in alcoholism. Alcohol Health and Research World, 19,108-113. 

Another functional approach is the use of multiple recording sites on the skull to detect global changes in cortical activity through EEG. Event-related potentials (ERPs) derived from EEGs recorded during complex cognitive tasks have been... 

Kiefer, M., Schuch, S., Schenck, W., Fiedler, K. (2007). Emotion and memory Event-related potential indices predictive for subsequent successful memory depend on the emotional mood state. Advances in Cognitive Psychology, 5(3), 363-373. 

Coles, M. G. H., Rugg, M. D. (1995). Event-related brain potentials An introduction. In M. D. Rugg M. G. H. Coles (Eds.), Electrophysiology of mind Event-related brain potentials and cognition (pp. 1-26). New York Oxford University Press. 

Nunez-Pena, M. I., Aznar-Casanova, J. A. (2009). Mental rotation of mirrored letters Evidence from event-related brain potentials. Brain and Cognition, 69, 180-187. 

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