Cognitive decline in elderly

Reducing benzodiazepine use in elderly patients is important for several reasons. Long-term use of benzodiazepines can accelerate cognitive decline in elderly patients (Paterniti et al. 2002). The elderly experience excessive sedation from benzodiazepines compared with younger individuals (Lechin et al. 1996). Benzodiazepine use by elderly patients are not only associated with cognitive side effects... 

A controlled study demonstrated efficacy against treatment-resistant depression associated with cognitive decline in elderly patients who had previously failed to respond to therapeutic trials of standard synthetic anti-depressants or other phytomedicinal preparations, including St. John s Wort. Patients experienced significant sustained improvements in mood and cognitive performance. 

Ho RC, Cheung MW, Fu E, Win HH, Zaw MH, Ng A, Mak A (2011) Is high homocysteine level a risk facfau fiw cognitive decline in elderly A sysiranatic review, metaanalysis, and meta-regression. Am J Geriatr Psychiatry 19 607-617... 

Cenacchi B, Bertoldin T, Farina C, Fiori MG and Crepaldi G (1993). Cognitive decline in the elderly A double blind, placebo-controlled multicenter study on efficacy of phosphati-dylserine administration. Aging, Clinical and Experimental Research, 5, 123-133. 

Barker A, Jones R, Prior J, Wesnes K. (1998). Scopolamine-induced cognitive impairment as a predictor of cognitive decline in healthy elderly volunteers a 6-year follow-up. IntJ Geriatr Psychiatry. 13(4) 244-47. 

Paterniti S, Dufouil C, Alperovitch A. Long-term benzodiazepine use and cognitive decline in the elderly the epidemiology of vascular aging study. J Clin Psychopharmacol 2002 22(3) 285-93. 

McCaddon A, Hudson P, Davies G, Hughes A, Williams IH, Wilkinson C. Homocysteine and cognitive decline in healthy elderly. Dement Geriatr Cogn Disord 2001 12 309-313. 

Despite evidence for an association between low B vitamins status and cognitive decline in the elderly, a role for B vitamins supplementation is not... 

Fioravanti, M., Ferrario, E., Massaia, M., Cappa, G., Rivolta, G., Grossi, E., and Buckley, A.E., 1997. Low folate levels in the cognitive decline of elderly patients and the efficacy of folate as a treatment for improving memory deficits. Archives of Gerontology and Geriatrics. 26 1-13. 

In elderly patients with cognitive decline, significantly more favorable... 

When an elderly, physically healthy person shows a generalized decline in cognitive functioning that causes significant impairment in social or occupational functioning and represents a significant decline from a previous... 

Losartan was proved to be more effective for stroke prevention in patients with hypertension and LVH than the beta adrenoceptor blocker atenolol in the LIFE Study [8]. Furthermore, losartan in a comparative trial with hydrochlorothiazide/ atenolol [38], valsartan [39] were shown to inhibit the cognitive decline associated with hypertension in the elderly patients. 

Listen, stranger this was myself this was 1. (W. Faulkner, very last sentence in The Jail ) Alzheimer s disease has prevalence estimates of approximately 10% in individuals over age 65 and 30% in individuals over age 85 in the United States. Clinically AD presents as a progressive deterioration of selective cognitive domains, with initial symptoms indicating a decline in memory function, particularly a loss of episodic memory, which is considered a subcategory of declarative memory. But it is also well documented that a large number of elderly people have poorer memory performances, with prevalence of up to 40% in individuals over 60 years (Hanninen et al.,... 

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