Stimulants cocaine-related

Crack Cocaine Street Names Freebase. Mexican speedballs (crack w/ methamphetamine), roosten tornado (ovct 40 street slang terms) Use Crack is cocaine that comes in a rock crystal that can be heated and its vapors smoked. The tOTn crack ref s to the crackling sound heard when it is heated Actions CNS stimulant induces euphoria. Highly addictive Effects Acute CV or cerebrovascular emergencies (heart attack or stroke), could result in sudden death. Cocaine-related deaths are often a result of cardiac arrest or seizure followed by resp arrest (see also Cocaine)... 

Cocaine is a CNS stimulant that affects blood vessels and pupils, and increases body temperature, heart rate, and blood pressure. The euphoric effects of cocaine are quick and include reduced fatigue and mental clarity, as well as hyperstimulation. Research reports that the faster the absorption, the shorter the duration of action. The effects of cocaine in humans are variable (e.g., feeling of restlessness, irritability, and anxiety). Cocaine has powerful neuropsychological-reinforcing properties that are responsible for its repeated compulsive use. In some cases, the first dose may prove fatal. Cocaine-related death may be due to cardiac arrest or convulsion followed by respiratory arrest. In drug abuse, people mix cocaine with alcohol, leading to a chemical complex called cocaethylene, which intensifies the euphoria but can culminate in death. 

The higher than expected frequencies of alcohol PCP - and heroin PCP-related deaths also would have occurred if the combinations were preferred by the users. The motivation may involve the injection of heroin to moderate the adverse effects of PCP, or the use of PCP to ease the pain of heroin withdrawal. Another explanation assumes a stimulant effect of PCP. The use of stimulants, especially cocaine, with heroin is increasingly popular among heroin users (Kozel et al. 1982). 

The association of substance abuse with emergency department (ED) visits in 21 different metropolitan areas in the United States is reported by the Drug Abuse Warning Network (DAWN). This survey tracks ED visits that are due to a condition induced by or related to drug use. Included in the data are ED visits associated with alcohol, alone and in combination with other substances of abuse, including cocaine, heroin, marijuana, and major stimulants. Figure 33-2 indicates the number of ED visits that are associated with illicit... 

The answer is local anesthetic properties it can block the initiation or conduction of a nerve impulse. It is biotransformed by plasma esterases to inactive products. In addition, cocaine blocks the reuptake of norepinephrine. This action produces CNS stimulant effects including euphoria, excitement, and restlessness Peripherally, cocaine produces sympathomimetic effects including tachycardia and vasoconstriction. Death from acute overdose can be from respiratory depression or cardiac failure Cocaine is an ester of benzoic acid and is closely related to the structure of atropine. 

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