Citrus junos

The biological activity of flavonoids has attracted much interest in the part twenty years and a few compounds of this class have been shown to have AChEI effects. The flavanone naringenin (74) from Citrus junos (Rutaceae) ameliorated scopolamine-induced amnesia in mice, which may be related to an antiAChE effect, since naringenin was shown to inhibit AChE in vitro dose dependently. A recent theoretical study has shown that flavonoids and xanthones exhibit polyvalent effects such as antioxidant, amyloid reduction and cholinesterase inhibition, which made them interesting candidates for further studies. 

Heo HJ, Kim MJ, Lee JM, etal, Naringenin from Citrus junos has an inhibitory effect on acetylchoHnestetase and a mitigating effect on amnesia, Dement Geriatr Cogn Disord 17 151-157, 2004. 

Yuzu Citrus junos Dimethyl trisulfide, 6-methyl-5-hepten-2-ol(147), (Z)-9-dodecen-12-olide (148), 8-methylnonanal, 8-methyldecanal 167... 

Maruyama, T., Ito, M. and Honda, G. (2001) Molecular cloning, functional expression and characterization of (E)-beta farnesene synthase from Citrus junos. Biol. Pharm. Bull, 24,1171-5. 

Page 25, footnote, line 2. For Citrus Junes read Citrus junos. ... 

Synthesis of the hydroxyketones 127 and 128 was discussed in Volume 4 (p. 474, Refs. 163 and 164). The only novelty is that now both have been found in Yuzu (Citrus junos) oil, thus making ocimenol definitely naturally occurring. 

The biogenesis of those sesquiterpenes with a gem-dimethyl cyclopropane ring has been considered in terms of a precursor such as (384). This compound, bi-cyclogermacrene, has now been isolated from the peel oil of Citrus junos, together with germacrene-B and Bicycloelemene (385), previously isolated, is an... 

Occurrence E)-2-A. Cg-C,3 in citrus oils, especially bitter orange, Cg also in guava and ginger aromas, C, in bread, cucumber, carrot (see vegetable flavors) and rice flavor, c,o in coriander oil, butter, chicken and guava aroma, C,2 in coriander oil, peanut and meat flavor. (Z)-4-Heptenal is found, among others, in "butter, seafood and tea flavor, (Z)-3- and (Z)-6-nonenal in cucumber, melon and fish aroma, and (Z)-4-decenal in calamus oil and Citrus junos oil. ... 

Linalyl Derivatives.- The new linalyl derivatives (97) and (98) have been isolated from yudzu (Citrus junos) peel. A number of hydroxylated linalools (99) - (102) have been found in the Vitls... 

Hirota, R., Roger, N. N., Nakamura, H Song, H.-S., Suwamura, M., and Suganuma, N. (2010). Antiin ammatory effects of limonenen from Yuzu (Citrus junos Tanaka) essential oil and eosinophils.. 7 Food Sci. 75(3), H87-H92. 

Song, H.S., M. Sawamura, T. Ito, K. Kawashimo, and H. Ukeda, 2000. Quantitative determination and characteristic flavour of Citrus junos (yuzu) peel oU. Flavour Fragr. J., 15 245. 

Shinoda, N., M. Shiga, and K. Nishimura Constituents of Yuzu (Citrus junos) Oil. Agric. Biol. Chem. 34, 234 (1970). 

Bicycloelemene (227) has been isolated from Conocephalum conicum 313) and detected in both Jungermanniales and the Metzgeriales species 28). The enantiomer of (227) has been isolated from pepermint oil 339) and cold-pressed peel oil of Citrus junos 274, 302, 317). 

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