Chronic eosinophilic pneumonia

Eosinophilic infiltrations have been described with tolbutamide (SEDA-8, 917 90), and chronic eosinophilic pneumonia has been described with chlorpropamide (91) and tolazamide (92). 

Bondi E, Slater S. Tolazamide-induced chronic eosinophilic pneumonia. Chest 1981 80(5) 652. 

Fig.26.19a,b. Chronic eosinophilic pneumonia in a 56-year-old man presenting with a 4-week history of cough and fever. Moderate blood eosinophilia is found in laboratory workup, a Axial CT image shows strikingly peripheral wedge-shaped airspace consolidations, b The upper lobe predominance of the consolidations is displayed on coronal CT image... 

Chronic eosinophilic pneumonia Acute eosinophilic pneumonia Lymphangioleiomyomatosis Langerhans cell histiocytosis Idiopathic pneumonia syndrome Inflammatory bowel disease Cryoglobulinemia Primary biliary cirrhosis... 

Pesci A, Bertorelli G, Manganelli P, et al. Bronchoalveolar lavage in chronic eosinophilic pneumonia. Analysis of six cases in comparison with other interstitial lung diseases. Respiration 1988 54(suppl) 16-22. 

Abbreviations. HRCT, high-resolution computed tomography CEP, chronic eosinophilic pneumonia. 

Figure 10 HRCT demonstrating predominantly peripheral airspace consolidation in a patient with CEP. Abbreviations HRCT, high-resolution computed tomography CEP, chronic eosinophilic pneumonia.

Marchand E, Cordier IF. Idiopathic chronic eosinophilic pneumonia. Semin Respir Crit Care Med 2006 27(2) 134-141. 

Jedeliinic PI, Sicihan L, Gaensler EA. Chronic eosinophilic pneumonia. A report of 19 cases and a review of the Uterature. Medicine (Baltimore) 1988 67(3) 154-162. 

Marchand E, Reynaud-Gaubert M, Lauque D, et al. Idiopathic chronic eosinophilic pneumonia. A cUnical and follow-up study of 62 cases. The Groupe d Etudes et de Recherche sur les Maladies OrpheUnes Pulmonaires (GERM 0 P). Medicine (Baltimore) 1998 77(5) 299-312. 

Naughton M, Fahy J, FitzGerald MX. Chronic eosinophilic pneumonia. A longterm follow-up of 12 patients. Chest 1993 103(1) 162-165. 

Ebara H, Ikezoe J, Johkoh T, et al. Chronic eosinophilic pneumonia evolution of chest radiograms and CT features. J Comput Assist Tomogr 1994 18(5) 737-744. 

Katoh S, Fukushima K, Matsumoto N, et al. Accumulation of CXCR3-expressing eosinophils and increased concentration of its ligands (IPIO and MIG) in bron-choalveolar lavage fluid of patients with chronic eosinophilic pneumonia. Int Arch Allergy Immunol 2005 137(3) 229-235. 

Diffuse alveolar damage (Acute respiratory distress s3mdrome) Organizing pneumonia Lymphocytic interstitial pneumonia Chronic eosinophilic pneumonia Apical fibrobullous disease Nodules... 

Idiopathic chronic eosinophilic pneumonia Idiopathic acute eosinophilic pneumonia Associated with systemic disease Churg-Strauss syndrome... 

Although nonprominent, some eosinophilic microabscesses and a nonnecrotizing vasculitis are common in idiopathic chronic eosinophilic pneumonia (ICEP) and idiopathic acute eosinophilic pneumonia (lAEP). Parenchymal necrosis or interstitial fibrosis is seldom present, and most eosinophilic pneumonias heal without major sequelae. 

The eosinophilic pneumonias may manifest by different clinical-imaging syndromes, namely Loffler syndrome, chronic eosinophilic pneumonia, or acute eosinophilic pneumonia, the diagnosis of which requires both characteristic clinical-radiological features and the demonstration of eosinophilia at BAL—or on histopathology—with or without peripheral blood eosinophilia. 

Figure 2 Idiopathic chronic eosinophilic pneumonia. Chest radiograph demonstrating bilateral opacities with ill-defined margins and predominating in the upper lobes, with density varying from ground glass to consoHdation.

Figure 3 Idiopathic chronic eosinophilic pneumonia. CT scan of the chest showing multifocal alveolar consolidation in the periphery of the lung.

Marchand E, Etienne-Mastroianni B, Chanez P, et al. Idiopathic chronic eosinophilic pneumonia and asthma how do they influence each other Eur Respir... 

Gaensler EA, Carrington CB. Peripheral opacities in chronic eosinophilic pneumonia the photographic negative of pulmonary edema. AJR 1977 128 1-13. 

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