Chromatography, rapid scanning

Barcelo, D., G. Durand, V. Bouvot, and M. Nielen (1993). Use of extraction disks for trace enrichment of various pesticides from river water and simulated seawater samples followed by liquid chromatography-rapid-scanning UV-visible and thermospray-mass spectrometry detection. Environ. Sci. Technol., 27(2) 271-277. 

Quantitative HPLC analysis was carried out on a Spectraphysics 8720 chromatography system, a rapid scan detector by Barspec on a Zorbax ODS column with acetonitrile water 75/25 as the eluent. 

Optical Spectroscopy General principles and overview, 246, 13 absorption and circular dichroism spectroscopy of nucleic acid duplexes and triplexes, 246, 19 circular dichroism, 246, 34 bioinorganic spectroscopy, 246, 71 magnetic circular dichroism, 246, 110 low-temperature spectroscopy, 246, 131 rapid-scanning ultraviolet/visible spectroscopy applied in stopped-flow studies, 246, 168 transient absorption spectroscopy in the study of processes and dynamics in biology, 246, 201 hole burning spectroscopy and physics of proteins, 246, 226 ultraviolet/visible spectroelectrochemistry of redox proteins, 246, 701 diode array detection in liquid chromatography, 246, 749. 

Mondello, L., Casilli, A., Tranchida, P.Q., Dugo, G., Dugo, P. (2005) Comprehensive two-dimensional gas chromatography in combination with rapid scanning quadrupole mass spectrometry in perfixme analysis. J. Chromatogr. A 1067 235-243. 

In general, the quadrupole instruments do not achieve the mass range and the high resolution of sector instruments. However, the mass range and resolution are adequate for unit-resolution mass spectrometry, and the rapid scan and sensitivity make them especially suitable for use with capillary gas chromatography (Fig. 2.46). 

Conventional spectrophotometers scan through a spectrum one wavelength at a time. Newer instruments record the entire spectrum at once in a fraction of a second. One application of rapid scanning is chromatography, in which the full spectrum of a compound is recorded in seconds as it emerges from the chromatography column. 

M. Zerezghi, K. Mulligan, et al., Application of a rapid scanning plasma emission detector and gas chromatography for multi-element quantification of halogenated hydrocarbons, J. Chromatogr. Sci., 22 348-352(1984). 

Reepmeyer, J. C., Revelle, L. K., and Vidavsky, I. (1998), Detection of clobetasol propionate as an undeclared steroid in zinc pyrithione formulations by high-performance liquid chromatography with rapid-scanning ultraviolet spectroscopy and mass spectrometry. Journal of Chromatography A, Vol. 828, Number 1,18 December 1998, pp. 239-246(8). 

Caudill, W.L. Ewing, A.G. Jones, S. Wightman, R.M. Liquid chromatography with rapid scanning electrochemical detection at carbon electrodes. Anal. Chem. 1983, 55, 1877-1881. 

Samuelsson, R. O Dea, J. Osteryoung, J. Rapid scan square wave voltammetric detector for high-performance hquid chromatography. Anal. Chem. 1980, 52, 2215-2216. 

W. L. Caudill, A. G. Ewing, S. Jones, and R. M. Wightman, Liquid Chromatography with Rapid Scanning Electrochemical Detection at Carbon Electrodes. Anal. Chem., 55 (1983) 1877. 

A drawback of this method involves the need for rapid scanning by the mass spectrometer. The instrument must determine the mass spectrum of each component in the mixture before the next component exits from the gas chromatography column, in order that one substance is not contaminated by the next fraction before its spectrum has been obtained. 

Other Specific Detectors. The most elegant of the specific detectors used for gas chromatography is the mass spectrometer. (This application of mass spectrometry was discussed in Chapter 16.) Infrared spectrometry has become a practical detection method, now that rapid-scan infrared systems have made collecting samples unnecessary. In fact, part of the impetus behind developing both these techniques was the difficulty in collecting gas chromatographic fractions vapor samples entering cold... 

It has been over 40 years since infrared spectroscopy was first applied to GC by identifying trapped effluents taken directly from the column. With the advances of FTIR spectrometers and computer techniques, these modern FTIR spectrometers and data systems provide rapid scanning, increased sensitivity, and endless disk space for data storage. All of these characteristics are necessary to merge FTIR with today s sensitive high-resolution capillary gas chromatography. Therefore, the reliability of qualitative analysis of GC/FTIR is greatly enhanced. 

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