Chloro platinum

Two examples of aquation/anation studies of chloro-platinum(II) complexes of possible medical relevance appeared in subsection 1 above 202,207). Aquation of cisplatin is slower in the presence of DNA but not in the presence of phosphate 220). DNA also inhibits substitution in [Pt(terpy)(py)]2+ and related complexes. For reaction of these charged complexes with iodide ion inhibition is attributable to electrostatic interactions - the complex is concentrated on the double helix and thus separated from the iodide, which distances itself from the helix. Intercalation of these complexes within the helix also serves to make nucleophilic approach by neutral reagents such as thiourea more difficult 221). 

Chloro platinum ylide complexes will undergo replacement of Cl for acetone in the presence of NaBPlu.437 The ylide complexes (35) undergo oxidative addition at platinum(II) by Mel, and substitution of pyridine by CO to give the carbonyl complex. The ylide ligand is not displaced.438... 

Chloride in ira ,y-bis[triphenylphosphane]arenetellurolato(chloro)platinum was exchanged for bromide, iodide, or thiocyanate1. 

The catalytically active cationic complex is preformed by reaction of complex 12 with the strong acid HCIO4 the phenolic oxygen is protonated and the coordinative bond of the bidentate vanillin ligand to platinum is cleaved at this end. In contrast to the treatment of 12 with HCl, which gives an inactive chloro-platinum complex, the non-coordinating anion [0104] leaves a vacant coordination site on the central metal, thus rendering it catalytically active. 

In 1936 K. A. Jensen (2, 3) measured the moments of a number of platinum (II) dihalido complexes with tertiary phosphines and other such hgands. He showed that the cis complexes had moments of up to about 11.0 Debye units (D) and that atom polarization in complex compounds is much higher than in organic compounds. He also showed that all the complexes of this type had had their cis or trans configurations incorrectly assigned on the basis of color, in analogy with the diammine di-chloro platinum (II) complexes. 

Related compounds of the type [Pt(SMe)(NH3)Cl]2 can be similarly synthesized by treatment of methylisothiourea with cis-[Pt(NH3)2Cl2], or directly via reaction between methanethiol and K[Pt(NH)3Cl3]. The C12p3/2 binding energies of cis- and trans-[Pt(SEt2)2Cl2] have been measured as part of an extensive study of chloro-platinum(ii) complexes. ... 

Other authors have measured Cl lp i2 binding energies for the [PtCljlbipy)] case, as part of an extensive investigation of chloro-platinum complexes. 

At the start of this work, x-ray diffraction studies had established that the only platinum coordination sites which existed in isolable compounds prepared by reaction of chloro-platinum complexes, including PtCt2(NH3)2 with purine and pyrimidine bases were N7 for guanosine (21), Nl and N7 for adenosine (22,23), N3 for cytidine (24) and no reaction with thymidine. 

The dinuclear Pt complex 193 reacts with bipy to afford the bis(acyl)hydrido(chloro)platinum(ii) complex, PtHCl(COR)2(bipy) 1043 which has been fully characterized, and 1043 undergoes reductive elimination of aldehyde to afford a Pt(ii) complex (Scheme... 

The kinetics and likely mechanism of reaction of the five-co-ordinate rhodium(iii) species [RhCl2H(PR3)o] with di-/ -chloro-platinum(ii) and -palladium(ii) complexes have been mentioned earlier in this chapter [see the section on palladium(ii)]. The mechanism of the reaction of [IrX(cod)(phen)] (X = Cl, I, or NCS) with ethylene-diamine involves the [Ir(cod)(en)(phen)]+ cation, presumably containing unidentate ethylenediamine, as an intermediate (Scheme 5). The rate-limiting step is the breakdown of this cation. 

Method- 3. From platinum metal or platinum residues. Dissolve the platinum metal or platinum residues in aqua regia, evaporate just to dryness several times with concentrated hydrochloric acid, dissolve the final residue in a httle water and precipitate as ammonium chloro-platinate with excess of saturated ammonium chloride solution. Filter and dry the precipitate at 100°. Then proceed according to Method 1. 

Several processes are available for the recovery of platinum and palladium from spent automotive or petroleum industry catalysts. These include the following. (/) Selective dissolution of the PGM from the ceramic support in aqua regia. Soluble chloro complexes of Pt, Pd, and Rh are formed, and reduction of these gives cmde PGM for further refining. (2) Dissolution of the catalyst support in sulfuric acid, in which platinum is insoluble. This... 

The solution should be free from the following, which either interfere or lead to an unsatisfactory deposit silver, mercury, bismuth, selenium, tellurium, arsenic, antimony, tin, molybdenum, gold and the platinum metals, thiocyanate, chloride, oxidising agents such as oxides of nitrogen, or excessive amounts of iron(III), nitrate or nitric acid. Chloride ion is avoided because Cu( I) is stabilised as a chloro-complex and remains in solution to be re-oxidised at the anode unless hydrazinium chloride is added as depolariser. 

C15H11ClN3Pt+ C10H13N5O7P- -2.25 H20 Chloro(terpyridyl)platinum(Il)adenosine 5 -monophosphate, TPTAMP 43 373... 

Both chloro ligands of [Pt2Cl2(/u-dppm)2] are replaced by quinoline, 1-methylimidazole, and 4-t-butylpyridine, but only one is replaced by 2,4,6-trimethylpyridine.109 All of these platinum(I) dimers and pt2(PPh3)2(/i-dppm)2] display solid-state luminescence at room temperature and long emission lifetimes at 77 K.109... 

Platinum(IV) complexes of phosphine and arsine ligands formed by oxidation with chlorine or bromine are well known. Chloro complexes such as ci5-[PtCl2(PEt3)4]2+ can be generated by electrolysis of the platinum(II) complex c -[PtCl2(PEt3)2].433 Similar platinum(IV) complexes... 

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