2-chloro-1 - ethanone

Acetonitrile, diphenyl-, 55, 94, 102 Acetonitrile, diphenyl-2-( 1 ethoxyvinyl) [Acetonitrile, diphenyl 2 (1 ethoxy ethenyl) ], 55, 102 Acetonitrile, phenyl-, 55, 91,94 Acetophenone, 4-chloro- [Ethanone, l-(4-chlorophenyl)-[, 55, 40... 

After the initial claim of the synthesis of an oxirene (by the oxidation of propyne Section 5.05.6.3.1) this system reappeared with the claim 31LA(490)20l) that 2-chloro-l,2-diphenyl-ethanone (110) reacted with sodium methoxide to give diphenyloxirene (111), but it was later shown (52JA2082) that the product was the prosaic methoxy ketone (112 Scheme 97) (the formation of 111 from 110 would be an a-elimination carbene-type reaction). Even with strong, nonnucleophilic bases, (110) failed to provide evidence of diphenyloxirene formation (64JA4866). 

Another type of elimination reaction is the reaction of 1 -(5-methyl-1 -phenyl- H-pyrazol-4-yl)ethanone with a Vilsmeier complex to give 3-chloro-3-(5-methyl-l-phenyl-l//-pyrazol-4-yl)propenal, which in turn undergoes dichloroformylation... 

Liao and Li enantioselectively synthesized and studied the antifungal activity of optically active miconazole and econazole. The key step was the enan-tioselective reduction of 2-chloro-l-(2,4-dichlorophenyl)ethanone catalyzed by chiral oxazaborolidine [10]. 

SYNS CAP CAP CHExMICALMACE CHLORACETOPHENONE co-CHLOROACETOPHEN-ONE 1-CHLOROACETOPHENONE CHLORO-ACETOPHENONE, Uquid or soUd (DOT) CHLORO-METHYL PHENAX KETONE 2-CHLORO-l-PHENYL-ETHANONE CN ETHANONE, 2-CHLORO-l-PHENYL- MACE (lachr> mator) NCI-C55107 PHENACYL CHLORIDE PHENYLCHLORO-METHYLKETONE... 

SYNS 4-CHLOROACETOPHENONE 4 -CHLOROACETOPHENONE l-(4-CHLORO-PHENYL)ETHANONE USAF DO-1... 

SYNS ETHANONE, 2-CHLORO-l-(9H-FLUOREN-2-YL)- FLUORENE, 2-(CHLOROACETYL)- KETONE, CHLOROMETHYL 2-FLUORENYL... 

C9H8CIFO 3-chloro-4 -fluoropropiophenone 347-93-3 25.00 1.2298 2 16251 C9H9BrO 2-bromo-1-(4-methylphenyl)ethanone 619-41-0 25.00 1.4298 2... 

C9H802 trans-cinnamic acid 140-10-3 573.15 50.955 1,2 16292 C9H9CIO 2-chloro-1-(4-methylphenyl)ethanone 4209-24-9 534.65 47.223 1.2... 

In a search for new anti-cancer agents Abdel-Rahman (92FA319) (Scheme 3) obtained dipyrazol-3-one derivative 15 by heating two equivalents of 5-aminopyr-azol-3-one 13 with 2-chloro-l-(piperazin-l-yl)ethanone derivative 14 in DMF. 

The McCoy method also allows the preparation of cyclopropylacylsilanes 33. Treatment of a-haloacylsilanes with lithium diisopropylamide (LDA) or with lithium tetramethylpiperidide (LUMP) affords enolates which combine with a variety of electrophilic olefins to produce cyclopropane derivatives33. The major diastereomers formed in the reactions of 2-chloro-l-(/er/-butyldimethylsilyl)ethanone are usually the civ-compounds, while the corresponding a-bromo acylsilane exhibits a higher degree of trans selectivity. 

Synthesis. - Hantzsch s Synthesis (Type A S—C—N + C-C) From thioureas. Starting from thioureas, the following compounds have been obtained 2-amino-4-(4-benzyloxyphenyl)thiazoles, 2-(2-amino-5-hydroxythiazol-4-yl)-1 -(4-chloro-3-methylphenyl)ethanone, 2-benzylidenehydrazino-4-( 1,5 -di-... 

Beilstein Handbook Reference) Acetophenone, 2-chloro- AI3-52322 BRN 0507950 Caswell No. 179C CCRIS 2370 Chemical mace Chloroacetophenone a-Chloroacetophenone 1-Chloroacetophenone 2-Chloro-1-phenylethanone 2-Chloroacetophenone Chloromethyl phenyl ketone CN CN (lacrimator) EINECS 208-531-1 EPA Pesticide Chemical Code 018001 Ethanone, 2-chloro-1-phenyl- HSDB 972 Mace (lacrimator) NCI-C55107 NSC 41666 ra-Chloroacetophenone Phenacyl chloride Phenacylchloride Phenylchloromethylketone UN1697. Pharmaceubcal intermediate. A lachrymator, is the primary component of Mace, a riot-control gas. Plates, mp = 56.5° bp = 247° d n 1,324 insoluble in H2O soluble in MezCO, petroleum ether, very soluble in EtOH, EtzO, C6H6, CS2 LDso (rat ori) = 127 mg/kg. Janssen Chimica Lancaster Synthesis Co. Penta Mfg. 

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