Chitosan-coated iron oxide

Hamed Arami, Zachary Stephen, Omid Veiseh and Miqin Zhang. (2011). Chitosan-Coated Iron Oxide Nanopartides for Molecular Imaging and Drug Delivery, Chitosan for biomaterials I, Advances in Polymer Science, Volume 243/2011,163-184, DOI 10.1007/12 2011 121. 

PEG-chitosan-coated iron oxide NPs with high saturated magnetization As carriers of 10-hydroxycamptothecin [212]... 

Qu JB, Shao HH, Jing GL, Huang F. PEG-chitosan-coated iron oxide nanopeuticles with high saturated magnetization as carriers of 10-hydroxycamptothecin Preparation, characterization and cytotoxicity studies. Colloids Surf B Biointerfaces. 2013 102 37-44. 

Chitosan-Coated Iron Oxide Nanoparticles for Molecular Imaging and Drug Delivery... 

PEI-PEG-chitosan copolymer-coated iron-oxide nanoparticles Chemical co-precipitation Gene delivery [240]... 

Kievit FM, Veiseh O, Bhattarai N et al (2009) PEI-PEG-Chitosan copolymer coated iron-oxide nanoparticles for safe gene delivery synthesis, complexation, and transfection. Adv Funct Mater 19 2244—2251... 

Another strategy (which could be related to seeded emulsion polymerization) was recently developed by Ding et al. [142,143] to promote the formation of polymer chains close to the surface of iron oxides. The procedure, based on the formation of polymer-monomer pairs, was the following PVA-coated Fc304 nanoparticles were mixed with chitosan (CS) and AA polymer-monomer pair to form micelles... 

Juang, J.H., Wang, J.J., Shen, C.R., Kuo, C.H., Chien, Y.W., Kuo, H.Y., et al Magnetic Resonance Imaging of Transplanted Mouse Islets Labeled With Chitosan-Coated Superparamagnetic Iron Oxide Nanoparticles. Transpl. P. 42, 2104—2108... 

Recently, Reddy et al. demonstrated that labeling of mesenchymal stem cells (MSCs) with superparamagnetic iron oxide nanoparticles (SPlONs) coated with chitosan did not alter the proliferation, surface marker expression or differentiation capacity of MSCs [92]. For comparison, Resovist, a commercially available MR contrast agent coated with carboxydextran, showed alteration to the chondrogenesis capacity of MSC. In addition, the chitosan-coated SPION-loaded MSCs did not show any toxic effects in viability studies over a 3-week period. Further, in vivo MR imaging of the chitosan-coated SPION-loaded MSCs injected into the brain of an ischemic brain rabbit model enabled the tracking of the stem cells for up to 2 weeks (Fig. 2). 

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