Children’s Hospital, Boston

Can any number of identical subunits be accommodated in the asymmetric unit while preserving specificity of interactions within an icosahedral arrangement This question was answered by Don Caspar then at Children s Hospital, Boston, and Aaron Klug in Cambridge, England, who showed in a classical paper in 1962 that only certain multiples (1, 3, 4, 7...) of 60 subunits are likely to occur. They called these multiples triangulation numbers, T. Icosahedral virus structures are frequently referred to in terms of their trian-gulation numbers a T = 3 virus structure therefore implies that the number of subunits in the icosahedral shell is 3 x 60 = 180. 

Children s Hospital Boston Professor of Neurology (Pediatrics),... 

Director, Clinical Chemistry Department of Laboratory Medicine Children s Hospital Boston,... 

R. M. Jimenez, MD S. Connolly, MD Department/Division Radiology, Area of Clinical Expertise, Musculoskeletal Radiology, Children s Hospital Boston, Department of Radiology, 300 Longwood Avenue, Main 2, Boston, MA 02115, USA... 

Fran Rohr, MS, RD Division of Genetics and Genomics, Boston Children s Hospital, Boston, MA, USA... 

John W. Graef, M.D., Chief Emeritus, Lead and Toxicity Program, Children s Hospital, Boston... 

Agency for Toxic Substance and Disease Registry (ATSDR), U. S. Department of Health and Human Services, Toxicological Profile for Lead (1993) 129 John W. Graef, M.D., Children s Hospital, Boston, personal interviews, August 1996. 

Kathy Maloof, LISCW, Massachusetts Department of Public Health, personal interview, 28 Aug. 1996 Beth Holleran, LICSW, Children s Hospital, Boston, personal interview, 21 Aug. 1996. 

The Case. For 14 years in a row US News t World Report rated Children s Hospital Boston as one of the top pediatric facilities in the countiy. It is the largest pediatric medical center in the United States and, as the primaiy pediatric teaching hospital for Harvard Medical School, many of the hospital s staff also hold faculty positions at the university. You could say that Children s Hospital specializes in specialization. With such a wide array of pediatric specialists, the hospital treats many of the most challenging and medically complex young patients in the country. 

Children s Hospital, Boston, 178, 185-7 Children s Hospital, Minnesota, 241 Clarity Team, 323 Clinton Administration decision-making processes, 148 history of NASA, 29, 30, 32, 33, 65, 69, 313... 

Children s Hospital Boston and Harvard Medical School, Vascular Biology Program, Department of Surgery, 1 Blackfan Circle, Karp Family Research Laboratories, Floor 12, Boston, Massachusetts 02115, USA... 

My daughter Lindsey graduated from Rensselaer Polytechnic Institute with a Bachelor of Science in biomedical engineering. She followed that up with a PhD in biology. My son-in-law, Brian Polizzotti, is a PhD engineer/instructor at MIT and Harvard Medical School at Children s Hospital Boston. We talk often about polymers, plastics, and materials. 

At 48 hours after birth, psychologists certified in the use of the NBAS by the Child Development Unit of Children s Hospital, Boston, MA administered the NBAS to the infant in the hospital. The test was administered again in the subject s home at 15 and 30 days after birth. 

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