Chemotherapy, for cancer treatments

Chemotherapy for cancer treatment is widespread, and a wide range of natural as well as synthetic materials are known. One of the effective chemotherapies is the treatment with molecular targeting drugs. They are designed to bind to a specific... 

Bleomycin (BLM) was first isolated as a copper complex from a culture of Streptomyces verticillus. Since then numerous analogs have been prepared by modifying the conditions of fermentation. Bleomycins (114, bleomycin A2) are used clinically in combination cancer chemotherapy for the treatment of head and neck cancer, certain lymphomas, and testicular cancer (555). 

Also of clinical importance, radiation or chemotherapy for the treatment of cancer can cause damage to the vilU in the intestine, probably as a result of DNA damage in the... 

First-line chemotherapy for the treatment of metastatic breast cancer is now largely dependent on the patient s HER-2 antigen status. The HER-2 (human epidermal growth factor receptor 2) protein is overexpressed on the surface of breast cancer cells in approximately 15-25% of patients. The measurement of this protein can be performed by immunohistochemistry methods, where the degree of protein expression is denoted by negative, 1+, 2+ or 3+. As Mrs CR s has HER-2,3+ disease, this denotes strong protein overexpression. 

The FDA, in 1985, gave approval for the use of two psychoactive chemicals from marijuana to prevent nausea and vomiting after chemotherapy in cancer treatment. THC can be prescribed in capsule form for these patients. Research suggests that compounds, other than THC, inhaled when smoking marijuana can also be used for medicinal purposes. Marijuana may help stop the weight loss in AIDS patients, it might lower eye pressnre in people with glaucoma, it may control spasms in multiple sclerosis patients, and it could be used to relieve chronic pain. 

Hahm HA, Armstrong DK, Chen TL, Grochow L, Passos-Coelho J, Goodman SN, Davidson NE, Kennedy MJ. Novobiocin in combination with high-dose chemotherapy for the treatment of advanced breast cancer a phase 2 study. Biol Blood Marrow Transplant 2000 6(3A) 335 3. 

Kaufman D, Chabner BA. Clinical strategies for cancer treatment The role of drugs, in Chabner BA, Longo DL, eds. Cancer Chemotherapy and Biotherapy Principles and Practice. Philadelphia, Lippincott-Raven, 1996 1-16. 

Currently, there are six major methods available for cancer treatment surgery, radiotherapy, chemotherapy, immunotherapy, hyperthermia, and photodynamic therapy. The first three are the most widely used, and the last three are under development. Surgery, radiotherapy, hyperthermia, and photodynamic therapy are primarily local, while chemotherapy and immunotherapy are primarily systemic methods. In most cases a combination of methods is used for cancer treatment. Except for surgery, the application of the remaining five methods can be improved considerably by developing quantitative understanding of mass and/or heat transfer in tumors and normal tissues. In what follows, we will discuss the problems and promises of each of these five techniques from the point of view of mass and heat transfer, and mention anti-angiogenic approaches. 

Antifolate chemotherapy occupies a Special place in the history of cancer treatment, as this class of drugs produced the first striking, although temporary, remissions in leukemia, and the first cure of a solid tumor, choriocarcinoma. These advances provided great impetus to the development of chemotherapy for cancer. Interest in folate... 

The client has received five treatments of combination chemotherapy for cancer of the lung. Which data indicates the medications are effective ... 

In the last decades, many approaches have been tried for the treatment of cancers. The most common therapies so far are surgery, radiation and chemotherapy or combination thereof. Despite significant improvements, these therapies still lack tumor specificity and can cause severe side effects. Therefore, developing new therapies and methods for cancer treatment is a demanding issue in medical science. 

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