Chemically induced resistance biochemicals

Chen, C. and Klaassen, C.D. (2004) Rat multidrug resistance protein 4 (Mrp4, Abcc4) molecular cloning, organ distribution, postnatal renal expression, and chemical inducibility. Biochemical and Biophysical Research Communications, 317, 46-53. 

Local infection of a plant will stimulate the development of natural defense mechanisms often resulting in an immune reaction toward a variety of pathogens. Certain chemicals can also trigger the same biochemical reactions in plants. Among the chemicals found to induce this systemic acquired resistance (SAR) are thieno[2,3-rf [ 1,2,3]-thiadiazoles 195 <1999JPR341>. 

In summary, then, whether acting alone or in conjunction with other chemicals, the unique and potent physiological, biochemical, and morphological effects Induced by the phytoecdysones confers an integral role for them in host plant resistance. 

Until 1999 Renilla GFP was the only biochemically well characterized fluorescent protein besides the Aequorea GFP. It proved to have a much higher extinction coefficient, resistance to pH-induced conformational changes and denaturation, and tendency to dimerize compared to Aequorea GFP [7]. However, chromophores from Aequorea and Renilla GFPs was shown to be chemically identical [7-9], indicating that the fluorescence properties of the proteins are depending on both, the chromophore and the corresponding environment provided by the amino-acid backbone. 

Our evidence supports the contention that plant oxidative enzjnmes can be used as constitutive and/or inducible antinutritive bases of resistance against insects. This resistance is based on the irreversible chemical degradation of multiple essential or limiting nutrients, which may be more difficult for the insect species to evolve biochemical resistance against than against classical "toxins". 

---