Chaetomium spp

Saito T, Suzuki Y, Koyama K, Natori S, litaka Y, Kinosita T (1988) Chetracin A and Chaetocin B and C, Three New Epipoiythiodioxo-piperazines fi om Chaetomium spp. Chem Pharm Bull 36 1942... 

Sekita S, Yoshihira K, Natori S, Udagawa S, Sakabe F, Kurata K, Umeda M (1982) Chaetoglobosins, Cytotoxic 10-(Indol-3-yl)-[13]cytochalasans from Chaetomium spp. I. Production, Isolation and Some Cytological Effects of Chaetoglobosins A-J. Chem Pharm Bull 30 1609... 

Other important epoxides are postulated in the biosyntheses of pheromones derived from epoxide intermediates like the insect pheromone a-(—)-(75, 2/ ,45, 5/ )-multistriatin [6]. Here again the enantioselectivity of the epoxidation is essential for the biological activity of the compounds. The fungus Chaetomium cochlioides rearranges enantiospecif-ically the epoxide 13 of a fatty acid precursor 12 to a branched aldehyde 14 (Fig. 4), an epoxide rearrangement step also reported from other pathways. This intermediate aldehyde is reduced to the alcohol 15 and gives, after another epoxidation step, the tetrahydrofiiran derivative 17 found as a secondary metabolite in a number of Chaetomium spp. [7]. 

Degradation Fusarium spp., aspergillus flavus, aureobasidium spp., chaetomium globosum Penicillium funiculosum, paecilomyces variotii, trichoderma viride... 

The other major genera that were isolated on a less frequent basis in the survey included many of the same field fungi that have been isolated from commercial tobacco samples such as Alternaria spp.> Rhizopus nigricans Fusarium spp., Cladosporium> Chaetomium> Trichoderma viride> Phoma spp., and Mucor spp. (Table A). These field fungi invade the substrate prior to harvest and require an abundance of moisture (at least 24% to 25%) on the substrate in order to support their growth (Christensen and Kaufman, 1965). 

From E. caryophyllata, Leconora rupicola, Chaetomium thielavioideum, and Cylindrocarpon spp. Used as a 0.02M MeOH soln. for extraction-photometric detn. of Ti (A ax 515 nm). Prisms (EtOH or Me2CO). Sol. MeOH. Mp 162°. 

---