Glucose utilization cerebral

Crosby, G., Crane, A. M. Sokoloff, L. (1982). Local changes in cerebral glucose utilization during ketamine anesthesia. Anesthesiology 56, 437-43. 

Maquet P., Dive D., Salmon E. et al. (1992). Cerebral glucose utilization during stage 2 sleep in man. Brain Res. 571, 149-53. 

Vannucci, S. J., Clark, R. R., Koehler-Stec, E. etal. Glucose transporter expression in brain relationship to cerebral glucose utilization. Dev. Neurosci. 20 369-379,1998. 

Sokoloff, L., Reivich, M., Kennedy, C. etal. The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization theory, procedure, and normal values in the conscious and anesthetized albino rat. J. Neurochem. 28 897-916,1977. 

Nehlig A, Lucignani G, Kadekaro M, Porrino U, Sokoloff L. (1984). Effects of acute administration of caffeine on local cerebral glucose utilization in the rat. EurJ Pharmacol. 101(1-2) 91-100. 

Schroeder H, Boyet S, Nehlig A. (1989). Effects of caffeine and doxapram perfusion on local cerebral glucose utilization in conscious rats. EurJ Pharmacol. 167(2) 245-54. 

Duverger D, DeFeudis FV, Drieu K. (1995). Effects of repeated treatments with an extract of Ginkgo biloba (EGb 761) on cerebral glucose utilization in the rat an autoradiographic study. Gen Pharmacol. 26(6) 1375-83. 

London ED, ConnoUy RJ, Szikszay M, Wamsley JK, Dam M (1988) Effects of nicotine on local cerebral glucose utilization in the rat, J Neurosci 8 3920-3928 Markou A (2008) Neurobiology of nicotine dependence, Phil Trans R Soc B 363 3159-3168 Marks Ml, Stitzel JA, Romm E, Wehner JM, Collins AC (1986) Nicotinic binding sites in rat and mouse brain comparison of acetylchohne, nicotine, and alpha-bungarotoxin. Mol Pharmacol 30 427 36... 

London E, Fanelh RJ, Kimes A, et al Effects of chronic nicotine on cerebral glucose utilization in the rat. Brain Res 520 208-214, 1990 Lonnqvist J, Sihvo S, Syvalahti E, et al Moclobemide and fluoxetine in atypical depression a double-blind trial. J Affect Disord 32 169-177, 1994 Loo H, Malka R, Defance R, et al Tianeptine and amitriptyline controlled double-blind trial in depressed alcoholic patients. Neuropsychobiology 19 79-85, 1988... 

As shown in Figure (1), injected [uC]2-deoxy-D-glucose ([UC]DG) is transported toward cerebral tissue through the Mood brain barrier and then phosphorylated into [MC]DG-diphosphate ([l4C]DG-6P), which accumulates in the cells. Measuring radioactivity in brain sections by autoradiography, it is possible to calculate local cerebral glucose utilization (LCGU) [116]. 

McCulloch J., Savaki H. E., Jehle J., and Sokoloff L. (1982) Local cerebral glucose utilization in hypothermic and hyperthermic rats. J. Neurochem. 39, 255-258. 

Yoshino A., Hovda D. A., Kawamata T., Katayama Y., and Becker D. P. (1991) Dynamic changes in local cerebral glucose utilization following cerebral conclusion in rats evidence of a hyper- and subsequent hypometabolic state. Brain Res. 561, 106-119. 

Morelli M, Pontieri F, Linfante I, Orzi F, Di Chiara G (1993c) Local cerebral glucose utilization after Dl receptor stimulation in 6-OHDA lesioned rats effect of sensitization (priming) with a dopaminergic agonist. Synapse 73 264-269... 

Changes in local cerebral glucose utilization induced by convulsants. Neuroscience 14 823-35. 

Suzuki, R., Yamaguchi, T., Kirino, T., Orzi, F., and Klatzo, I., The effects of 5-minute ischemia in Mongolian gerbils. I. Blood-brain barrier, cerebral blood flow, and local cerebral glucose utilization changes, Acta Neuropathol., 60, 207, 1983. 

Lu DM, Davis DW, Mans AM, Hawkins RA (1983) Regional cerebral glucose utilization measured with [ Cjgluco.se in brief experiments. Am J Physiol 245.C428-C438. 

Freedland CS, Whitlow CT, MUler MD, Porrino LJ (2002) Dose-dependent effects of delta9-tetrahydrocannabinol on rates of local cerebral glucose utilization in rat. Synapse 45 134-142... 

Noronha JG, Larson DM, Rapoport SL Regional cerebral incorporation of plasma [14-C]palmitate, and cerebral glucose utilization in water-deprived Long-Evans and Brattleboro rats. Exp Nemol 1989 103 267-276. 

An investigation of the cardiovascular effects of 117 in dogs found that use of a low dose continual infusion, rather than a bolus administration, may reduce undesirable cardiovascular effects [336]. Arecoline increased mean arterial blood pressure [337] and selectively increased local cerebral glucose utilization in the hippocampus and median raphe [338], In general, the effect of 117 on local cerebral blood flow and glucose utilization correlated well, but uncoupled effects were observed in some regions, such as the hippocampus [339]. 

Kennedy, C., Sakurada, O., Shinohara, M., Jehle, J. and Sok-oloff, L. (1978) Local cerebral glucose utilization in the normal conscious Macaque monkey. Ann. Neurol. 4 293-301. 

Substrate Utilization. Quantitative measurement of regional substrate utilization in vivo is well within the capability of PET, but is of somewhat greater conceptual complexity than the measurement of regional blood volume. Such measurements are exemplified by the quantitative studies of cerebral glucose utilization using C-labeled glucose (IS) and F-labeled 2-deoxy-D-glucose (14). 

Pazdernik TL, Cross RS, Giesler M, Samson FE, Nelson SR. Changes in local cerebral glucose utilization induced by convulsants. Neuroscience. 1985 14 823-835. 

Keifer MC, Firestone J (2007) Neurotoxicity of pesticides. J Agromedidne 12 17-25 Kimbrell TA, Ketter TA, George MS, Little JT, Benson BE, l fiUis MW, Herscovitch P, Post RM (2002) Regional cerebral glucose utilization in patients with a range of severities of unipolar depression. Biol Psychiatry 51 237-252... 

---