Cerebral accident

Cardiovascular The hyperdynamic circulation caused by hydralazine may accentuate specific cardiovascular inadequacies. It may reduce the pressor responses to epinephrine. Postural hypotension may result from hydralazine. Use with caution in patients with cerebral vascular accidents. 

Adverse reactions may include headache depression arrhythmia syncope heart block cerebral vascular accident cerebral ischemia CHF palpitation nausea hypersensitivity, including localized and generalized rash bronchospasm respiratory failure eratitis blepharoptosis visual disturbances including refractive changes diplopia ptosis. 

Contraindications Convulsive disorders, cardiovascular impairment, head injury or cerebral vascular accident, severe hypertension, mechanical ventilation disorders, hypersensitivity to doxapram. 

Cardiac reactions (including ischemia, coronary artery vasospasm, and Ml), and noncardiac vasospasm-related reactions (such as cerebral hemorrhage and cerebrovascular accident CVA ), occur rarely, particularly in patients with hypertension, diabetes, ora strongfamily history of coronary artery disease obese patients smokers males older than 40 years and postmenopausal women. 

It is indicated in spasticity due to neurological disorders e.g., multiple sclerosis, chronic myelopathy, degenerative diseases of the spinal cord, cerebrovascular accidents and cerebral palsy painful muscle spasm associated with static and functional disorders of the spine (cervical and lumbar syndromes) painful muscle spasm following surgery e.g., for herniated intervertebral disc or for osteoarthritis of the hip. 

Humbert G, Delaunay P, Leroy J, Robert M, Schuhl IF, Poussin A, Augustin P. Accident vasculaire cerebral au cours d un traitement par les gonadotrophines. [Cerebrovascular accident during treatment with gonadotropins.] Nouv Presse Med 1973 2(l) 28-30. 

Chopard JL, Moulin T, Bourrin JC, et al. Contraception orale et accident vasculaire cerebral ischemique. Semin Hop (Paris) 1988 64 2075. 

The effects of chronic hypertension on the human organism are, with one exception, of little interest to the investigator studying pathogenesis, although of great import to the sufferer and his physician. That exception is failure of the kidneys. Disease and failure of the heart are probably caused by chronic overstrain, often associated with another metabolic disease, arteriosclerosis of the coronary arteries. They account for about two thirds of the deaths primarily due to hypertension. Strokes of apoplexy, or cerebral vascular accidents, from rupture or thrombosis of a cerebral artery weakened by disease cause another sixth, uremia about one twelfth, and other conditions the remainder (28). Except for uremia, these events are usually the result of overwork and increased arterial tension. Only rarely does the heart escape hypertrophy. 

Q1 Stroke, or a cerebrovascular accident, is a serious disturbance of the brain s circulation (cerebral circulation) and is the third most frequent cause of... 

Other studies have found evidence of harmful effects, however, although some of these have been criticized. For example, a study published some years after the accident reported that forty-two of fifty-five residents studied had poor psychomotor performance. There were acknowledged flaws in the design of this study, which were beyond the control of the authors, but the conclusion was that aluminium poisoning probably led to long term cerebral impairment in some people in Camelford . 

Because the enlarged cortex of humans is not shared by most nonhuman species, using animal models to study the functions of the cortex is more difficult. Much of what we know about the cerebral cortex then has come V from unfortunate accidents and diseases such as strokes... 

Amyotrophic lateral sclerosis Myasthenia gravis Parkinson s disease Alzheimer s disease Cerebral palsy Cerebral vascular accident Brain tumors... 

Impending Cerebral Vascular Accident 71-year-old man with sudden onset, two hours previously, of confusion, paralysis and weakness on left side of body and drooling and unable to speak distinctly. Initial blood pressure 190/100, pulse normal. Given 250 ml of 0.3 percent H202 started immediately. Comment. All symptoms significantly improved within 30 minutes and completely resolved after one hour. Patient did not return for follow-up evaluation, but was asymptomatic with blood pressure of 140/90 when he left the office. 

Cerebral ischaemia is responsible for approximately 85% of strokes (cerebrovascular accidents) irrespective of whether they are thrombotic or embolic in nature.4 Reestablishment of blood flow (reperfusion) in the postischaemic period is often accompanied by further tissue injury that is associated with aberrant microvascular function, damage to endothelial cells, and inflammatory cell exudates.5-6 In recent years, particular attention has focused upon the contribution of neutrophils to the pathogenesis of the reperfusion injury seen in cerebral ischaemia. 

---