Cell adhesions polymers, polymer brushes

Keywords protein adsorption cell adhesion polymer brush surface modification biofouling PEO a-chymotrypsin IgG... 

Keywords Assay Bioactive surface Cell adhesion Cell chip Hydrogel Microengineering Micropattern Peptide Polymer brush Protein adsorption... 

Xue et al. have investigated the effect of graft PIPAAm brnsh density on the resulting cell adhesion character in terms of the number and occnpied area of adhered cells, and the circularity of the cells, and they find the correlation of the polymer graft density with cell attachment and detachment character (Choi et al., 2012 Xue et al., 2012). They prepare TRCS on a self-assembled monolayer formed silicon surface, where various polymer densities are grafted by using surfaces initiated ATRP method. On TRCS with a dense polymer brush (0.11 chains/nm ), a lower circularity is found in attached cells having an extremely poor cell adhesive character. When the polymer... 

Takahashi, H., Matsuzaka, N., Nakayama, M., Kikuchi, A., Yamato, M., Okano, T. (2012). Terminally functionalized thermoresponsive polymer brushes for simultaneously promoting cell adhesion and cell sheet harvest Biomacromolecules, 13, 253—260. 

Raynor, J. E., Capadona, J. R., CoUard, D. M., Petrie, T. A., and Garcia A. J. 2009. Polymer brushes and self-assembled monolayers versatile platforms to control cell adhesion to biomaterials. Biointerphases 4 FA3-FA16. 

SECM lithography of PS brushes, (a) Schematic representation of the local oxidative patterning of PS polymer brushes by a SECM tip electrogenerating Ag + ions in 3M aqueous HNOj. (b) Selective sorting of myofibroblastic and macrophage cells of heterogeneous population of peritoneal cell from their selective adhesion, respectively, onto oxidized PS pattern and on pristine PS. (From Ktari, N., et al., Langmuir, 26,17348-17356,2010.)... 

Suppression of Cell Adhesion on Concentrated Polymer Brushes... 

Yoshikawa, C., Hashimoto, Y, Hattori, S., Honda, T., Zhang, K., Terada, D., Kishida, A., Tsujii, Y, and Kobayashi, H. 2010. Suppression of cell adhesion on well-defined concentrated polymer brushes of hydrophilic polymers. 

Polymer Brushes as Substrates for the Integrin Specific Adhesion of Human Umbilical Vein Endothelial Cells, 2007,28,2536-2546. 

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