Cathartics cascara sagrada

Emodin cathartics Cascara sagrada Senna Rhubarb Aloe... 

Cascara sagrada is used as a cathartic. It is most useful when prepared as a fluid extract, and tends to be a mild laxative causing Htfle discomfort. However, on prolonged use it may result in characteristic melanotic pigmentation of the rectal mucosa. The bitter taste can be lessened, owing to neutralization of the acid constituents, if the ground substance is moistened and mixed with magnesium or calcium hydroxide. This treatment may lessen the potency of the preparation. 

C Calcium and iron supplementation are common causes of constipation. Polycarbophil, a bulk-forming laxative, exerts its therapeutic effect by increasing the mass and water content of stool and by speeding transit time in the colon. Cascara sagrada and sennosides are cathartics, which speed colonic transit time and alter water and electrolyte transport across the colonic mucosa. Sodium biphosphonate is a saline cathartic, which increases intestinal peristalsis by osmotic properties. Docusate sodium is a stool... 

Irritant agents used in the treatment of constipation include cascara, sagrada, castor oil, senna, rhubarb, phenol-phthalein, and acetphenolisatin. Phenolphthalein is a constituent of many OTC preparations, including Ex-Lax and Feen-A-Mint. Most of these agents, with the exception of castor oil, are slow in their onset of action (24 hours). Castor oil is hydrolyzed to ricinoleic acid, the active cathartic. It has an onset of action of 2 to 6 hours. 

Cascara sagrada Rhamnus purshiana Cathartic in some diet aids Abdominal cramps, diarrhea fluid and electrolyte loss. 

Anthraquinone glycosides have long been used medicinally as cathartics and laxatives. Plant-derived drugs of this type include aloes Aloe species), cascara sagrada (Rhamnus purshiams), frangula (Rhamnus frangula), rhubarb (Rheum officinale), rumex or yellow dock (Rumex crispus) and senna (Cassia spp.). Many of the commercial preparations (patent medicines) based on these plants are readily available. 

---