Cat-scratch disease

Suggested Alternatives for Differential Diagnosis Scarlet fever, cellulitis, cat scratch disease, gas gangrene, necrotizing fasciitis, tick-borne diseases such as Rocky Mountain spotted fever, pneumonia, septic shock, acute respiratory distress syndrome (ARDS), disseminated intravascular coagulation. 

B. abortus, brucellosis), Flavobacterium, Gluconobacter, Legionella (L. pneumophila, Legionnaire s disease), Methylomonas, Neisseria (N. gonorrhea, gonorrhea), Pseudomonas, Rhizobium, Thermus, Xanthomonas, Rochalimaea (R. henselae, cat scratch disease)... 

K, in osteoclasts 619 Cations. See also Individual ions active transport 422 channels 421,422 Cat scratch disease 7 Cauliflower mosaic virus 247 CD (Cluster of Differentiation) 187,407 Cech, Thomas R. 84 CED-3 619 Cell(s)... 

Cat-scratch disease is caused by Bartonella henselae or B. quintana, which are gram-negative bacteria. It is transmitted through a cat scratch, bite, or lick and may cause a neuroretinitis with variable effect on visual acuity. The Bartonella species organisms are susceptible to a number of antibiotics. Systemic steroids can be used as an adjimctive treatment. 

F., Cadranel, J.F., Neuenschwander, S., Nocton, F. Hepatic and splenic involvement in cat-scratch disease imaging features. Abdom. Imag. 2000 25 102-183... 

G. D., Rothbanm, R.J., Wear, D.J., Rosenblnm, J.L. Granulomatous hepatitis associated with cat scratch disease. Lancet 1988/1 1132—1136... 

Rocco, V.K., Roman, R.J., Eigenbrodt, E.H Cat scratch disease. Report of a case with hepatic lesions and a brief review of the literature. Gastroenterology 1985 89 1400-1406... 

Includes, but not limited to Brown recluse spider bite Cat-scratch disease Cellulitis... 

Bartonella are slow-growing, fastidious gram-negative, Warthin-Starry-stained bacteria associated with bacillary angiomatosis, peliosis hepatis, cat-scratch disease,... 

FIGURE 3.16 Photomicrograph of a lymph node biopsy from a patient with cat-scratch disease showing abundant extracellular, clumped coccobacilli of B. henselae in necrotic foci. (Immunoalkaline phosphatase with monoclonal antibody against 6. henselae, naph-thol fast red substrate and hematoxylin counterstain x200.) Courtesy of Dr. Sulmln Qlu, University of Texas Medical Branch. 

Min KW, Reed JA, Welch DF, et al. Morphologically variable bacilli of cat scratch disease are identified by immunohistochemical labeling with antibodies to Rochalimaea henselae. Am Clin Pathol. 1994 101 607-610. 

Qian X, Jin L, Hayden RT, et al. Diagnosis of cat scratch disease with Bartonella henselae infection in formalin-fixed paraffin-embedded tissues by two different PCR assays. Diagn Mol Pathol. 2005 14 146-151. 

There is a single case report of a patient with AIDS-related bacillary angiomatosis that responded to azithromycin [302]. Chia and colleagues [303] described the successful treatment of eight of nine cases of cat-scratch disease in normal hosts with azithromycin. 

Two rather interesting racemic syntheses for allylic methylated fatty acids have been recently accomplished [15]. One of these corresponds to the intriguing (12 )-11-methyl-12-octadecenoic acid (6), a marine bacterial fatty acid that in most reported identifications from natural sources has been shown to have the E double bond stereochemistry, but both Z,E isomers have been synthesized [15]. This mainly bacterial fatty acid was initially isolated from Byrsocarpus coccineus seed oil [16], but later it was reported in a bacterium associated with cat scratch disease [17], in Mycobacterium fallax [18], and most recently in a Pseudomonas sp. (.Alteromonas) associated with both the toxic dinoflagellate Ostreopsis lenticularis and several Caribbean Palythoa species [15]. More recently, acid 6 has been identified as an intermediate in the biosynthesis of the bacterial acid 10,13-epoxy-l l-methyloctadeca-10,12-dienoic acid, a furan fatty acid identified in several marine bacteria such as Shewanella putrefaciens [19-20]. 

Lyme disease Tuberculous meningitis Fungal meningitis Rocky Mountain spotted fever Cat scratch disease... 

Cat-scratch disease is an abscess-forming reticular lymphadenitis. Electron microscopy showed rodshaped, elliptical or round bacteria in the extracellular spaced between degenerated cells of the lymph nodes (Ohtani et al. 1992). 

Fig. 8 37a,b. Epitrochlear lymphadenopathies in two different individuals with a active cat-scratch disease and b without any signs of infectious or inflammatory abnormalities. In a, the inflamed node is completely hypoechoic (arrowheads) with loss of definition of the echogenic hilum and appears surrounded by abnormally hyperechoic fat (arrows) due to perinodal cellulitis. In b, massive adipose infiltration has occurred in an epitrochlear lymph node (arrowheads) leading to a broad hyperechoic medulla. The cortical portion is markedly reduced in thickness and appears as a thin peripheral hypoechoic rim (arrows)... 

Carcia CJ, Varela C, Abarca K et al (2000) Regional lymphade-nopathy in cat-scratch disease ultrasonographic findings. Pediatr Radiol 30 640-643... 

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