Carriers release from

This section contains a review of results on the extensive study of defect states in the mobility gap of amorphous As- and Sb-containing chalcogenide semiconductors by relaxation technique. For extracting typical features, elemental selenium and simple compositions with relatively low content of arsenic and antimony are exemplified as possible. We will try to attribute TSDC peaks to charge carriers released from the respective trapping levels in the band gap of these materials. 

Although two peaks of comparable amplitude are presented (see Fig. 2.1), only the first, denoted as Mi, is actually related to the carriers release from trap, the second, denoted as M2, is connected with dark conductivity variation with temperature (DC conductivity-determined relaxation peak related to the movement of equilibrium carriers). 

The soluble electron carriers released from the reaction centers into the cytoplasm of bacteria or into the stroma of chloroplasts are reduced single-electron carriers. Bacterial ferredoxin with two Fe4S4 clusters is formed by bacteria if enough iron is present. In its absence flavodoxin (Chapter 15), which may carry either one or two electrons, is used. In chloroplasts the carrier is the soluble chloroplast ferredoxin (Fig. 16-16,C), which contains one Fe2S2 center. Reduced ferredoxin transfers electrons to NADP+ (Eq. 15-28) via ferredoxin NADP oxidoreductase, a flavoprotein of known three-dimensional structure.367 369... 

Two types of immobilization are used for immobilizing glucose isomerase. The intracellular enzyme is either immobilized within the bacterial cells to produce a whole-ceU product, or the enzyme is released from the cells, recovered, and immobilized onto an inert carrier. An example of the whole-ceU process is one in which cells are dismpted by homogenization, cross-linked with glutaraldehyde, flocculated using a cationic flocculent, and extmded (42). 

In a second example, a cell—gelatin mixture is cross-linked with glutaraldehyde (43). When soluble enzyme is used for binding, the enzyme is first released from the cell, then recovered and concentrated. Examples of this type of immobilization include binding enzyme to a DEAE-ceUulose—titanium dioxide—polystyrene carrier (44) or absorbing enzyme onto alumina followed by cross-linking with glutaraldehyde (45,46). 

In the classical set-up of bulk liquid membranes, the membrane phase is a well-mixed bulk phase instead of an immobilized phase within a pore or film. The principle comprises enantioselective extraction from the feed phase to the carrier phase, and subsequently the carrier releases the enantiomer into the receiving phase. As formation and dissociation of the chiral complex occur at different locations, suitable conditions for absorption and desorption can be established. In order to allow for effective mass transport between the different liquid phases involved, hollow fiber... 

Virtually all energy released from the oxidation of carbohydrate, fat, and protein is made available in mitochondria as reducing equivalents (—H or e ). These are funneled into the respiratory chain, where they are passed down a redox gradient of carriers to their final reaction with oxygen to form water. 

Although a portion of the nutrients released from feedstuff s is absorbed by diffusing across the apical membrane of enterocytes or through the junctional complexes of adjacent enterocytes (paracellular absorption), the majority of nutrients are absorbed from the lumen of the GIT by carrier proteins that are inserted into the apical membrane of enterocytes and colonocytes. 

The first step uses a 66 kDa albumin-like molecule as carrier (VNPr-U), from which the acidic conditions of the trank mucus (VNPr-D) will detach the urinary ligands. The carriers in the trank contents are additional OBPs which then preferentially bind the lipophylic ligands (L) released from their urinary vehicle. Once deposited at the VN-duct entrance, a third transporter (VNPr-D) completes the final movement into the organ (Rasmussen, pers. comm., 2001). 

Several important assumptions have been implicitly incorporated in Eqs. (15) and (16). First, these equations describe the release of a drug from a carrier of a thin planar geometry, equivalent equations for release from thick slabs, cylinders, and spheres have been derived (Crank and Park, 1968). It should also be emphasized that in the above written form of Fick s law, the diffusion coefficient is assumed to be independent of concentration. This assumption, while not conceptually correct, has been... 

Absorption Across the Skin. An aqueous carrier may be used for a variety of dermal products. In fact, carriers can be designed to limit the transportation of the penetration of the active ingredient (such as an insect repellent), if the desired effect is to keep the activity on the surface of the skin. Once again, however, only those materials that are dissolved will be available for penetration across the skin to gain access to the systemic circulation. For almost all chemicals in or about to enter commerce, dermal penetration is a passive process. The relative thickness of the skin makes absorption (into the systemic circulation) slower than the absorption across the GI or pulmonary barriers. This is compounded by the fact that the stratum comeum ftmction is to be impervious to the environment. One of the skin s major functions is protection from infection. Once a chemical penetrates into the dermis, it may partition into the subcutaneous fat. Essentially, absorption across the skin is a two-step process with the first being penetration and deposition into the skin and the second being release from the skin into the systemic circulation. The pattern of blood levels obtained via dermal penetration is generally one with a delayed... 

Drug release can be defined as the fraction of drug released from the nanoparticulate system as a function of time after the system has been administered [203]. The release of drug from nanoparticles depends on the location and physical state of the drug loaded into the colloidal carrier [133]. The drug can be released by ... 

Assembly of vims particles and release from the cell. Vims particles are assembled in infected cells from the new genetic material and viral proteins. Depending on the vims, there are different fates for an infected cell. With many vimses, the infected ceils are killed or lysed at the end of the infection. These vimses are called lytic. Other vimses do not kill the infected cell, but they establish a carrier state in which the cell survives and continually produces vims particles. These vimses are called nonlytic. Some vimses can also establish a case called latency in cells. In these situations, the vims s genetic material remains hidden in the cell, but no vims is produced. At a later time, the latent vims can become reactivated, and the cell will begin to produce infectious particles again. 

Environmental releases of PCBs often accompany releases of carriers from utility equipment. An example would be mineral oil released from oil filled transformers. When PCBs are present in a mineral oil-PCB mixture the aqueous solubility of the PCBs is reduced significantly. Two factors play a role in this reduction partitioning of the lipophilic (oil-loving) PCBs into the oil phase, and the reduced interaction of the PCBs with precipitation or groundwater caused by the hydrophobic nature of the oil matrix. Interpretation of aqueous PCB concentrations in the field must consider the presence of dissolved organic carbon (DOC) [382,386,397,403]. 

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