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High-grade neuroendocrine carcinoma

Pryor JG, Simon R, Bourne PA, et al. Merkel cell carcinoma expresses K homology domain-containing protein over expressed in cancer similar to other high grade neuroendocrine carcinomas. Hum Pathol. 2009 40 238-243. [Pg.338]

Neuroendocrine carcinoma, high grade, ampulla of Vater 0 88 38... [Pg.381]

Proliferation marker Ki-67 (MIB-1 clone) has been used to determine low-grade versus high-grade neuroendocrine carcinomas as reported by Lin and associates. The authors stated that when MIB-1 immunoreactiv-ity was considered, all low-grade neuroendocrine neoplasms showed immunoreactivity in less than 25% of the neoplastic cells in contrast to high-grade neuroendocrine neoplasms that showed MIB-1 immunoreactivity in greater than 50% of the neoplastic cells. [Pg.406]

FIGURE 14.5 Differential staining patterns of basaloid-patterned esophageal carcinomas. ACC, adenoid cystic carcinoma BSCC, basaloid squamous cell carcinoma HG NEC, high-grade neuroendocrine carcinoma. [Pg.504]

High-grade neuroendocrine carcinomas of the GI tract are rare. Those that arise in the esophagus are described above under neuroendocrine tumors of the esophagus, since most neuroendocrine tumors of the esophagus are high grade. [Pg.523]

High-grade neuroendocrine carcinomas in the colon and rectum most commonly occur as a component of poorly differentiated adenocarcinomas more than 50% of the tumor should show neuroendocrine differentiation in order to be called a neuroendocrine carcinoma. Both small cell and non-small cell types exist, and both tend to stain with low-molecular-weight cytokeratin (CAM5.2) in a perinuclear dot pattern, as well as with synaptophysin, chromogranin, and/or NSE (Fig. 14.32). ° ° GDI 17 stains a substantial minority of high-grade neuroendocrine carcinomas however, immunoreactivity has not been linked to c-kit juxta-membrane (exon 11) mutations. [Pg.523]

High-grade neuroendocrine carcinomas with necrosis and/or greater than 10 mitosis per 10 high power... [Pg.562]

High-grade neuroendocrine carcinoma versus lymphoma Immunohistochemical positivity for keratin and negative staining for lymphoid markers help exclude lymphoma. [Pg.565]

High-grade neuroendocrine carcinoma versus poorly differentiated nonendocrine cancer By im-... [Pg.565]

Jun SR, Lee JM, Han JK, Choi Bl. High-grade neuroendocrine carcinomas of the gallbladder and bile duct report of four cases with pathological correlation. J Comput Assist Tomogr. 2006 30 604-609. [Pg.586]

Nassar H, Albores-Saavedra J, Klimstra DS. High-grade neuroendocrine carcinoma of the ampulla of vater a clinicopatho-logic and immunohistochemical analysis of 14 cases. Am J Surg Pathol. 2005 29 588-594. [Pg.587]

Small-cell and high-grade neuroendocrine carcinoma of GIT ... [Pg.30]

High-grade (small cell) neuroendocrine carcinoma is diffusely synaptophysin and CK7 positive. [Pg.504]

HIGH-GRADE (POORLY DIFFERENTIATED) NEUROENDOCRINE CARCINOMAS... [Pg.523]

High-grade, poorly differentiated neuroendocrine carcinomas of the duodenum occur primarily in the region of the papilla of Vater and are covered in detail in Chapter 15. [Pg.523]

FIGURE 14.32 High-grade colonic neuroendocrine carcinoma with focal, moderate synaptophysin reactivity. [Pg.523]

High-grade (poorly differentiated) small cell and nonsmall cell neuroendocrine carcinomas can occur throughout the gastrointestinal tract but are rare. [Pg.523]

See other pages where High-grade neuroendocrine carcinoma is mentioned: [Pg.337]    [Pg.403]    [Pg.406]    [Pg.414]    [Pg.415]    [Pg.415]    [Pg.500]    [Pg.504]    [Pg.504]    [Pg.519]    [Pg.523]    [Pg.562]    [Pg.564]    [Pg.564]    [Pg.565]    [Pg.565]    [Pg.565]    [Pg.575]    [Pg.148]    [Pg.22]    [Pg.372]    [Pg.519]    [Pg.572]    [Pg.472]    [Pg.105]    [Pg.411]    [Pg.558]   
See also in sourсe #XX -- [ Pg.523 ]



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