Carboxin

Thenoyltrifluoroacetone and carboxin and its derivatives specifically block Complex II, the succinate-UQ reductase. Antimycin, an antibiotic produced by Streptomyees griseus inhibits the UQ-cytochrome c reductase by blocking electron transfer between bn and coenzyme Q in the Q site. Myxothiazol inhibits the same complex by acting at the site. 

The fungicide Carboxin has received some study, but with varied results. A 0.43 mM solution gave protection at 5-10 days in white bean, a 0.36% spray gave no protection to pinto or tempo bean, and a 0.01% spray increased injury to azalea. Soil applications of Carboxin were generally more beneficial, but results were still varied. A Carboxin soil amendment was phytotoxic to tobacco and pinto bean, although protection was noted in pinto bean. Pinto and tempo bean were protected from oxidant for 36-40 days after a soil amendment with Carboxin... 

Bean, cultivar Pinto Ozone Carboxin (2.3 ppm in soil) Fungicide 95 407... 

Bean, cultivars Tempo and Pinto Oxidant Carboxin (10% granular as soil amendment, 8 g/5-m row) Fungicide 100 305... 

Curtis, L. R., L. V. Edgington, and G. Hofstra. Relationship of ozone injury to time of application of carboxin analogues. Phytopathology 63 200, 1973. (abstract)... 

Taylor, G. S., and S. Rich. Ozone injury to tobacco in the field influenced by soil treatments with benomyl and carboxin. Phytopathology 64 814-817, 1974. 

CASRN 5234-68-4 molecular formula C12H13NO2S FW 235.31 Biological. The sulfoxidation of carboxin to carboxin sulfoxide by the fungus Ustilago maydis was reported by Bollag and Liu (1990). 

Soil. Carboxin oxidized in soil forming carboxin sulfoxide. The half-life in soil was reported to be 24 h (Worthing and Hance, 1991). 

Plant. In plants (barley, cotton and wheat) and water, carboxin oxidizes to the corresponding sulfoxide (Worthing and Hance, 1991). 

Fig. 15.7 Sulfoxidation of carboxine by the fungus Ustilage maydis. (Bollag and Liu 1990)...

There are many compounds in the carboxamide group. Carboxin, the lead product, is used extensively as a seed treatment in a wide variety of crops. Fenfuram and methfuroxam, produced by the substitution of the... 

Carboximide, trichloromethylthio-biocidal activity mechanism, 1, 400-401 fungicide, 1, 399 Carboximides as fungicides, 1, 194 Carboxin... 

Total U.S. annual production of all arylides combined is estimated to be 12,000—13,000 metric tons. The laigest volume arylide is AAA (acetoacetanilide) for Pigment Yellow 12 as well as for carboxin. The list price of AAA at the end of 1992 was 3.40/kg. 

Farrow et al. [159] determined the systemic fungicide carboxin (2,3-dihy-dro-6-methyl-5-phenylcarbamoyl-l,4-oxathiin), which is used in barley and wheat seed treatment of cereals. 

The carboxin is extracted from the sample with acetone in a Soxhlet extraction apparatus and, after concentration of the extract, is determined via gas-liquid chromatography using a nitrogen-selective detector. The presence of carboxin is confirmed by the use of a sulfur flame photometric detector. Recoveries ranged from 73 to 80% (barley) and 73 to 78% (wheat). 

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