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Additions carbonyl compounds

Reactions 11-22-11-26 involve the introduction of a CH2Z group, where Z is halogen, hydroxyl, amino, or alkylthio. They are all FriedeI-Crafts reactions of aldehydes and ketones and, with respect to the carbonyl compound, additions to the C=0 double bond. They follow mechanisms discussed in Chapter 16. [Pg.719]

Addition of vinylic organometallic compounds to unsaturated carbonyl compounds addition of organometallic compounds to acetylenic carbonyl compounds... [Pg.1691]

Anionic phosphorus has been used as well in a number of recent reports of additions to carbonyl compounds. Addition of dialkyl phosphite to aromatic aldehydes in the presence of catalytic amounts of La-BINOL and dilithium (R)-binaphthoxide occurs enantioselec-... [Pg.60]

Carbonyl compounds addition to, 73 659 a-alkylation of, 73 658s reduction with alumina—sodium borohydride, 76 572-573 reduction with aluminum alkoxides, 76 572... [Pg.144]

Carbon-nitrogen bond formation, by reductive amination, 59, 1 Carbon-phosphorus bond formation, 36, 2 Carbonyl compounds, addition of... [Pg.586]

In this section as well as in Section 10.5.3, carbonyl compounds that contain a stereocenter in the position a to the C=0 group are referred to succinctly with the term oc-chiral carbonyl compound. Because of the presence of the stereocenter, the half-spaces on both sides of the plane of the C=0 double bond of these compounds are diastereotopic. In this section, we will study in detail stereogenic addition reactions of hydride donors to the C=0 double bond of oc-chiral carbonyl compounds. Additions of this type can take place faster from one half-space than from the other—that is, they can be diastereoselective. [Pg.411]

Conversion of Phosphorus- or Sulfur-Stabilized C Nucleophiles with Carbonyl Compounds Addition-induced Condensations... [Pg.457]

Metal enolate complexes have also been used to catalyze the allylation of carbonyl compounds ° °, addition of aldehydes to l,3-dienes ° and alkynes as well as the addition of alkenes to alkynes " and indoles ". In the latter study, 5 mol% of Pd(acac)2 (29) and 10 mol% of PPhs were found to be an effective catalyst system for the coupling of Ai-methylindole (93) with a variety of 2-acetoxymethyl-substituted electron-deficient alkenes, including methyl 2-(acetoxymethyl)acrylate (94) (equation 26). Substituted indoles (95) constitute an important class of biologically active natural products and synthetic routes to these valuable compounds have therefore attracted considerable attention. [Pg.565]

A complementary entry to hydroxyalkylated products has been opened by deprotonation, carbonyl compound addition and ring-opening as outlined in equation 100 . The resulting y-lactols are precursors to y-butyrolactones or tetrahydrofuran derivatives. [Pg.403]

B. Addition to Carbonyl Compounds - Addition of metalated carboxylic acids to aldehydes and ketones affords a useful and versatile alternative to the Reformatsky reaction.42 The reaction is sensitive to steric effects... [Pg.282]

Modern aspects of electrophilic aromatic substitution chemistry address the development of enantioselective variants of these direct (hetero)arene functionalization reactions. For example, enantiomerically enriched metal catalysts, as well as organocatalysts, allowed for the asymmetric addition reactions of (hetero)arenes onto (a,P-unsaturated) carbonyl compounds. Additionally, highly enantioselective arylations of carbonyl compounds were accomplished with organometallic reagents... [Pg.6]


See other pages where Additions carbonyl compounds is mentioned: [Pg.49]    [Pg.49]    [Pg.3754]    [Pg.117]    [Pg.49]    [Pg.78]   
See also in sourсe #XX -- [ Pg.154 ]




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Addition of Allylboranes to Carbonyl Compounds

Addition of Chiral Enolates to Achiral Carbonyl Compounds

Addition of Nucleophiles to Carbonyl Compounds

Addition of Organometallic Reagents to Carbonyl Compounds

Addition of Organozincs to Carbonyl Compounds

Addition of a-Carbonyl Compounds

Addition of alcohols to carbonyl compounds

Addition of hydrocyanic acid to carbonyl compounds

Addition of hydrogen halide to unsaturated alcohols, ethers, carbonyl compounds, and nitriles

Addition of organomagnesium compounds to carbonyl groups

Addition reactions to carbonyl compounds

Addition to a,-unsaturated Carbonyl Compounds

Addition to carbonyl compounds

Addition, Condensation and Substitution Reactions of Carbonyl Compounds

Additions to a,P-unsaturated carbonyl compounds

Alcohols addition to carbonyl compounds

Asymmetric additions to carbonyl compounds

Bisulfite, addition to carbonyl compound

Carbanions addition reactions with carbonyl compounds

Carbanions carbonyl compound addition reactions

Carbene complexes addition to carbonyl compounds

Carbene complexes carbonyl compound addition reactions

Carbonyl compound by conjugate addition

Carbonyl compounds 1,4-addition reactions with

Carbonyl compounds 1,4-addition reactions with cyanohydrin ethers

Carbonyl compounds 1,4-addition reactions with cyanohydrins

Carbonyl compounds 1,4-conjugate addition of hydrazones

Carbonyl compounds Grignard additions

Carbonyl compounds Grignard reagent addition

Carbonyl compounds Michael addition

Carbonyl compounds Michael addition acceptors

Carbonyl compounds addition of Grignard reagents and

Carbonyl compounds addition of organometallic

Carbonyl compounds addition reactions

Carbonyl compounds addition reactions with alcohols

Carbonyl compounds addition scaffolds

Carbonyl compounds addition to alkylaluminum

Carbonyl compounds addition, enzyme-catalyzed

Carbonyl compounds addition-elimination

Carbonyl compounds addition-elimination reactions

Carbonyl compounds by Michael addition

Carbonyl compounds conjugate addition

Carbonyl compounds conjugated, addition

Carbonyl compounds diastereoselective additions

Carbonyl compounds enantioselective addition

Carbonyl compounds heteroatom nucleophile addition

Carbonyl compounds hydride donor additions

Carbonyl compounds nucleophilic addition

Carbonyl compounds nucleophilic addition reactions

Carbonyl compounds organozinc compound additions

Carbonyl compounds phosphorus nucleophile addition

Carbonyl compounds reactivity towards nucleophilic addition, table

Carbonyl compounds stereoselective addition

Carbonyl compounds sulfone conjugate additions

Carbonyl compounds, a-benzyloxy nucleophilic addition reactions

Carbonyl compounds, addition organochromium reagents

Carbonyl compounds, addition reactions Wittig reaction

Carbonyl compounds, addition reactions acetal formation

Carbonyl compounds, addition reactions alcohols

Carbonyl compounds, addition reactions cyanohydrin formation

Carbonyl compounds, addition reactions enamine formation

Carbonyl compounds, addition reactions hydration

Carbonyl compounds, addition reactions imine formation

Carbonyl compounds, addition reactions overview

Carbonyl compounds, addition reactions simple reversible additions

Carbonyl compounds, addition reactions substituted imine formation

Carbonyl groups/compounds additions

Carbonyl, addition

Carbonylation additive

Condensation reactions, carbonyl compounds conjugate addition

Conjugate Addition to Carbonyl Compounds

Conjugate Addition to a,3-Unsaturated Carbonyl Compounds

Conjugate addition to unsaturated carbonyl compound

Crown ethers 1,2-additions to carbonyl compounds

Enantioselective Addition of Hydride Donors to Carbonyl Compounds

Functional group addition carbonyl compounds

Grignard reagents addition to carbonyl compounds

Hydrogen sulfide, addition with carbonyl compounds

Michael addition unsaturated carbonyl compound

Michael addition, acidic carbonyl compounds

Nitrogen stabilization carbonyl compound addition reactions

Nucleophilic Addition to Conjugated Carbonyl Compounds

Nucleophilic addition with carbonyl compounds

Nucleophilic additions to carbonyl compounds

Nucleophillic Additions to Carbonyl and Imine Compounds

Oxidative addition from carbonyl compounds

Perfluorinated carbonyl compounds, additions

Phosphorus compounds, addition carbonyl group

Reactions of Carbonyl Compounds Simple Reversible Additions

Reactivity of Carbonyl Compounds toward Addition

Silanes, allyltrimethylintramolecular additions carbonyl compounds

Subject addition to carbonyl compounds

Tetrahedral carbonyl addition compound

Unsaturated carbonyl compounds addition

Unsaturated carbonyl compounds conjugate additions

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