Carbohydrate-Protein-Based Glycoconjugate Vaccines

Some key aspects have to be considered when designing such synthetic vaccines because the immunogenic activity of the conjugate depends on the nature of the hapten, the loading onto the protein, and the characteristics of the carrier. In 

FIGURE 19.3 Traditionally proposed mechanism for immune response of (a) polysaccharide-based vaccines and (b) polysaccharide-protein conjugate-based vaccines. 

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