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Captopril tablets

S-Captopril (SCpt) (SQ-014534) and R-captopril (RCpt) (SQ-034459) were supplied by Bristol-Myers Squibb Pharmaceutical Research Institute (Princeton, NJ, USA). Novocaptopril tablets (25 mg S-captopril/ tablet) were supplied by Novopharma Ltd., Toronto, Canada. 2-Hydro-xy-3-trimethylammoniopropyl-/1-cyclodextrin was supplied by Wacker-Chemie GmbH (Germany). [Pg.990]

Iscan et al. compared a number of parameters of a specially formulated buccal bioadhesive captopril tablet with that of a conventional tablet. The buccal formulation provided controlled release of captopril with a smooth plasma level profile and a long duration of action however, its bioavailability was 40% via the buccal route as compared to 65% following an oral dose. This was attributed to the intestinal mucosa being more permeable than the buccal mucosa, and it was concluded that further work was required to improve its bioavailability. [Pg.1077]

Captopril Tablets (25 mg) Carbamazepine Tablets (200 mg) Carbonyl Iron + Manganese Sulfate +... [Pg.4]

Captopril Tablets Silica gel modified with UV—Vis quaternary ammonium 2-50 pg mL-1 Flow injection system mini-column at the injection port [495]... [Pg.369]

Ce(IV) Captopril (tablets) tiopronin (Ph) penicillamine (Ph) phenothiazines (fluphenazine levomepromazine methotrimeprazine trimeprazine tartrate) (Ph, urine, and plasma) furosemide (Ph) hydrochlorothiazide (Ph) analgin (tablets) phenacetinum (tablets) folic acid (Ph)... [Pg.1309]

Maltodextrins (dextrose equivalent (DE) 4.0-7.0, 13.0-17.0 and 16.5-19.5) are proposed as novel chiral selectors for the construction of EPMEs for S-captopril assay [36]. The EPMEs can be used reliably for the assay of S-captopril as raw material and from pharmaceutical formulations as Novocaptopril tablets, using direct potentiometry. The best response was obtained when maltodextrin with higher DE was used for the electrode s construction. The best enantioselectivity and stability in time was achieved for the lower DE maltodextrin. L-Proline was found to be the main interferent for all proposed electrodes. The surface of the electrodes can be regenerated by simply polishing, obtaining a fresh surface ready to be used in a new assay. [Pg.63]

The construction of the electrode is simple, fast and reproducible. The electrode proved to be useful for the determination of the enan-tiopurity of S-captopril—raw material as well as for the content uniformity test of Novocaptopril tablets, by direct potentiometric method. The reliability of the analytical information is assured by the RSD values obtained in the uniformity content test. [Pg.992]

CAPTOPRIL/HYDROCHLOROTHIAZIDE (Capozide 50/25 tablets 50 mg captopril and 25 mg hydrochlorothiazide)... [Pg.130]

Chan, D.S. Sato, A.K. Claybaugh, J.R. Degradation of captopril in solutions compounded from tablets and standard powder. Am. J.Hosp.Pharm., 1994,51,1205-1207 [stability-indicating tablets powder] Wakabayashi, H. Yamato, S. Nakajima, M. Shimada, K. Application of an electrochemical detector with a graphite electrode to liquid chromatographic determination of penicillamine and captopril in biological samples. J.Pharm.Biomed.Anal., 1994, 12, 1147-1152 [rat serum liver kidney SPE electrochemical detection LOD 20-300 pg, extracted penicillamine homocysteine (IS)]... [Pg.222]

Kirschbaum, J. Perlman, S. Analysis of captopril and hydrochlorothiazide combination tablet formulations by liquid chromatography. J.Pharm.Sci., 1984, 73, 686-687 Perrett, D. Rudge, S.R. Drury, P.L. Determination of captopril by an improved high-performance liquid chromatography-electrochemical assay. Biochem.Soc.Trans., 1984,12, 1059-1060 Toyooka, T. Imai, K. Kawahara, Y. Determination of toted captopril in dog plasma by HPLC after prelabeling with ammonium 7-fluorobenzo-2-oxa-l,3-diazole-4-sulfonate (SBD-F). J.Pharm. Biomed.Anal., 1984, 2, 473-479 [derivatization]... [Pg.223]


See other pages where Captopril tablets is mentioned: [Pg.77]    [Pg.45]    [Pg.59]    [Pg.1080]    [Pg.115]    [Pg.223]    [Pg.45]    [Pg.1320]    [Pg.223]    [Pg.77]    [Pg.45]    [Pg.59]    [Pg.1080]    [Pg.115]    [Pg.223]    [Pg.45]    [Pg.1320]    [Pg.223]    [Pg.680]    [Pg.99]    [Pg.247]    [Pg.316]    [Pg.525]    [Pg.143]    [Pg.92]    [Pg.698]    [Pg.680]    [Pg.399]    [Pg.22]    [Pg.698]    [Pg.1309]   
See also in sourсe #XX -- [ Pg.192 ]




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Captopril

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