Hydrochlorothiazide Captopril

CAPTOPRIL/HYDROCHLOROTHIAZIDE (Capozide 50/25 tablets 50 mg captopril and 25 mg hydrochlorothiazide)... [Pg.130]

ACE Inhibitor/Diuretic benazepril/hydrochlorothiazide, captopril/hydrochlorothiazide, enalapril/hydrochlorothiazide, fosinopril/hydrochlorothiazide, iisinoprii/hydrochiorothiazide, moexiprii/hydrochiorothiazide, and quinaprii/hydrochiorothiazide ACE Inhibitor/Calcium Channel Blocker benazeprii/amiodipine, enaiaprii/feiodipine, trandoiaprii/verapamii... [Pg.1129]

Acetazolamide, amprenavir, captopril, hydralazine, hydrochlorothiazide, methyldopa, procainamide, quinidine, ticlopidine, and triamterene... [Pg.120]

Methods for determination of thiol drugs (i.e., captopril [21-25], penicillamine [26-28], hydrochlorothiazide [24, 25, 29, 30], and tiopronin [31, 32]) have been developed. These methods are based on CL from a cerium (IV) oxidation system sensitized by adequate fluorophores such as quinine and rhodamine B. By using HPLC-coupled CL-flow-injection analysis method, tiopronin and its metabolite 2-mercaptopropionic acid in human urine were sensitively determined with the detection limits of 0.8 and 1 pM, respectively [32],... [Pg.421]

Note Aldactazide is spironolactone and hydrochlorothiazide Aldoril is methyldopa and hydrochlorothiazide Avalide is irbesartan and hydrochlorothiazide Capozide is captopril and hydrochlorothiazide Dyazide is triamterene and hydrochlorothiazide Maxzide is triamterene and hydrochlorothiazide Moduretic is amiloride and hydrochlorothiazide Prinizide is lisinopril and hydrochlorothiazide... [Pg.282]

Capozide hydrochlorothiazide, captopril carisoprodol Artifar, Carisoma, Myolax, Sanoma, Sodol, Soma,... [Pg.641]

Antiviral agents acyclovir, amantadine, azidofhymidine Diuretics furosemide, hydrochlorothiazide, efhacrynic acid ACE inhibitors captopril, enalapril, ramipril, delapril, quinapril Antineoplastics methotrexate, azathioprine, doxorubicin, 5-fluouracil Antiepileptics valproic acid (from Ref. [95])... [Pg.250]

Also analyzed acebutolol, acetaminophen, alprazolam, amphetamine, atenolol, betaxolol, brotizolam, caffeine, camazepam, captopril, chloroquine, clobazam, clomipramine, cloth-iapine, clotiazepam, cloxazolam, cocaine, codeine, diclofenac, dihydralazine, dihydrocodeine, dihydroergotamine, diphenhydramine, domperidone, doxepin, droperidol, ergota-mine, ethyl loflazepate, fenethylline, fluoxetine, flupentixol, flurazepam, furosemide, gliclazide, hydrochlorothiazide, hydroxyzine, ibuprofen, imipramine, ketazolam, loprazo-1am, lorazepam, lormetazepam, maprotUine, medazepam, mepyramine, methadone, methaqualone, methyldopa, methylphenidate, metoclopramide, metoprolol, mexiletine, mianserin, midazolam, minoxidil, morphine, nadolol, nitrazepam, oxprenolol, papaverine, pentazocine, phenprocoumon, phenylbutazone, pipamperone, piritramide, practolol, pra-zepam, prazosin, promazine, promethazine, propoxyphene, propranolol, prothipendyl, quinine, sotalol, sulpride, thioridazine, trazodone, triazolam, trimipramine, tripelennamine, lyramine, verapeunil, yohimbine... [Pg.74]

Kirschbaum, J. Perlman, S. Analysis of captopril and hydrochlorothiazide combination tablet formulations by liquid chromatography. J.Pharm.Sci., 1984, 73, 686-687 Perrett, D. Rudge, S.R. Drury, P.L. Determination of captopril by an improved high-performance liquid chromatography-electrochemical assay. Biochem.Soc.Trans., 1984,12, 1059-1060 Toyooka, T. Imai, K. Kawahara, Y. Determination of toted captopril in dog plasma by HPLC after prelabeling with ammonium 7-fluorobenzo-2-oxa-l,3-diazole-4-sulfonate (SBD-F). J.Pharm. Biomed.Anal., 1984, 2, 473-479 [derivatization]... [Pg.223]

Starting with a low dose of the ACE inhibitor reduces the risk of first-dose hypotension. In a study in 8 patients with hypertension, treated with a diuretic (mainly furosemide or hydrochlorothiazide) for at least 4 weeks, captopril was started in small increasing doses from 6.25 mg. Symptomatic postural hypotension was seen in 2 of the 8 patients, but was only mild and transient. ... [Pg.21]

The risk of ACE inhibitor-induced renal impairment in patients with or without renovascular disease can be potentiated by diuretics. " In an analysis of 74 patients who had been treated with captopril or lisinopril, reversible acute renal failure was more coimnon in those who were also treated with a diuretic (furosemide and/or hydrochlorothiazide) than those who were not (11 of 33 patients compared with 1 of 41 patients). Similarly, in a prescription-event monitoring study, enalapril was associated with raised creatinine or urea in 75 patients and it was thought to have contributed to the deterioration in renal function and subsequent deaths in 10 of these patients. However, 9 of these 10 were also receiving loop or thiazide diuretics, sometimes in high doses. Retrospective analysis of a controlled study in patients with hypertensive nephrosclerosis identified 8 of 34 patients who developed reversible renal impairment when treated with enalapril and various other antihypertensives including a diuretic (furosemide or hydrochlorothiazide). In contrast, 23 patients treated with placebo and various other antihypertensives did not develop renal impairment. Subsequently, enalapril was tolerated by 7 of the 8 patients without deterioration in renal function and 6 of these patients later received diuretics. One patient was again treated with enalapril with recurrence of renal impairment, but discontinuation of the diuretics (furosemide, hydrochlorothiazide, and triamterene) led to an improvement in renal function despite the continuation of enalapril. ... [Pg.21]

A retrospective analysis found that captopril, given to 6 patients on Dyazide (hydrochlorothiazide/triamterene), had not increased the potassium levels. ... [Pg.24]

In one study, sulindac 200 mg twice daily given to patients taking capto-pril 100 to 200 mg twice daily caused only a small rise in blood pressure (from 132/92 to 137/95 mmHg). Sulindac 150 mg twice daily did not attenuate the blood pressure response to captopril when it was substituted for ibuprofen in an elderly woman. Similarly, sulindac 200 mg twice daily did not blunt the antihypertensive effect of enalapril in 9 patients with hypertension. Two studies in black women also found that sulindac 200 mg twice daily for one month did not alter the antihypertensive effect of fosinopril 10 to 40 mg daily or lisinopril 10 to 40 mg daily (given with hydrochlorothiazide 25 mg daily). - ... [Pg.30]

A retrospective analysis of 14 patients without renal impairment taking potassium supplements and either furosemide or hydrochlorothiazide, found that the levels of serum potassium, during a 4-year period, had not significantly increased after the addition of captopril. Another study in 6 healthy subjects found that intravenous potassium chloride caused virtually the same rise in serum potassium levels in those given enalapril as in those given a placebo. ... [Pg.32]

A man who had been taking captopril and hydrochlorothiazide for 6 years and propafenone 300 mg daily for 4 years, without problems, and without any history of convulsive episodes, experienced a tonic-clonic seizure while watching television. It was later found that he had started to take two capsules of ketoconazole daily 2 days previously for the treatment of a candidal infection. The preliminary results of another study in 12 healthy subjects given a single 300-mg dose of propafenone with or without ketoconazole 200 mg found that the increase in propafenone AUC with ketoconazole was greater in those with lower cytochrome P450 isoenzyme CYP2D6 activity. ... [Pg.274]

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