Capping operation

The tray and caps operate as a unit or system therefore they must be so considered in design (Figures 8-63 and 8-66). 

Example 11.8 With highly reactive absorbents, the mass transfer resistance in the gas phase can be controlling. Determine the number of trays needed to reduce the CO2 concentration in a methane stream from 5% to 100 ppm (by volume), assuming the liquid mass transfer and reaction steps are fast. A 0.9-m diameter column is to be operated at 8 atm and 50°C with a gas feed rate of 0.2m /s. The trays are bubble caps operated with a 0.1-m liquid level. Literature correlations suggest = 0.002 m/s and A, = 20m per square meter of tray area. 

CAP OPERATING SURGICAL WOMEN BLUE MAIN BODY24IN DISPOSABLE 600S 6532013055341 PG 6656 ... 

The vibratory bowl and the tracks can be easily removed from the unit for cleaning and sterilization. The bulk caps are loaded into the vibratory bowl and conveyed to the capping-up stations. The capping operation is controlled by the no stopper/no cap sensor. If a stopper is not sensed at the station, a cap will not be placed on the vial. 

Identify and determine performance/evaluation criteria. A key element in validation is the determination of what constitutes acceptable output, along with the determination that the quality of output is consistent with a process that is in control. Under normal operating conditions, there should thus be little variability in the quality of the output. Examples of easily measured performance criteria for the validation of the capping operation are cap torque and misaligned caps. 

Once a vial has been filled with powder, it is stoppered and transported out of the sterile area, and is capped. The current regulatory trend is to perform the capping operation in a sterile area using sterilized caps. After capping, vials are usually visually inspected, labeled, and packaged. 

Samples and calibration standards are prepared for analysis using a 10-mL syringe. Add 10.00 mL of each sample and standard to separate 14-mL screw-cap vials containing 2.00 mL of pentane. Shake vigorously for 1 min to effect the separation. Wait 60 s for the phases to separate. Inject 3.0-pL aliquots of the pentane layer into a GC equipped with a 2-mm internal diameter, 2-m long glass column packed with a stationary phase of 10% squalane on a packing material of 80/100 mesh Chromosorb WAW. Operate the column at 67 °C and a flow rate of 25 mL/min. 

Good gas distribution is necessary for the bed to operate properly, and this requites that the pressure drop over the distributor be sufficient to prevent maldistribution arising from pressure fluctuations in the bed. Because gas issues from the distributor at a high velocity, care must also be taken to minimize particle attrition. Many distributor designs are used in fluidized beds. The most common ones are perforated plates, plates with caps, and pipe distributors. 

Nitrogen is used for pressure maintenance in oil and gas reservoirs for enhanced recovery. It is sometimes used as a miscible agent to reduce oil viscosity and increase recovery in deep reservoirs. Other appHcations include recovery of oil in attic formations, gas cap displacement, and a sweep gas for miscible CO2 slugs. Nitrogen competes with CO2, a more miscible gas with hydrocarbons (qv), in most of these appHcations. The production mode is typically by on-site cryogenic separation plants. In 1990, nitrogen production in enhanced recovery operations was 20 x 10 m /d (750 million SCF/d)... 

As reservoir pressure is reduced by oil production, additional recovery mechanisms may operate. One such mechanism is natural water drive. Water from an adjacent more highly pressured formation is forced into the oil-bearing formation by the pressure differential between the formations. Another mechanism is gas drive. Expansion of a gas cap above the oil as oil pressure declines can also drive additional oil to the wellbore. Produced gas may be reinjected to maintain gas cap pressure as is done on the Alaskan North Slope. Additional oil may also be produced by compaction of the reservoir rock as oil production reduces reservoir pressure. 

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