Capillary electrochromatography alternatives

LC is currently used extensively in the photographic industry. One application is to quantify some of the components of photographic paper. As demands to reduce analysis time increase, an analytical method that can give improved productivity is required. One possible alternative to LC is capillary electrochromatography (CEC). In a recent paper, this analytical protocol was applied to separate some color photographic paper components <2002MI1>. [Pg.297]

Reilly, J., and Saeed, M. (1998). Capillary electrochromatography as an alternative separation technique to high-performance liquid chromatography and capillary zone electrophoresis for the determination of drug related impurities in Lilly compound LY300164. /. Chromatogr. A 829, 175-186. [Pg.314]

Capillary electrochromatography (CEC) is a rapidly emerging technique that adds a new dimension to current separation science. The major "news" in this method is that the hydrodynamic flow of the eluting liquid, which is typical of HPLC, is replaced by a flow driven by electro-endoosmosis. This increases considerably the selection of available separation mechanisms. For example, combinations of traditional processes such as reversed-phase- or ion-exchange- separations with electromigration techniques are now possible. Also, CEC is opening new horizons in the separation of non-polar compounds, and thus represents an alternative to the widely used micellar electrokinetic chromatography. [Pg.6]

A wide variety of approaches are currently being used in the fabrication and technology of columns for capillary electrochromatography (CEC). Continuous polymer bed, or monolithic columns (see Section 3.4), manufactured by in-situ polymerization within the columns, have been used in numerous application areas and have been shown to be highly efficient. In a second approach, a sol-gel process is employed to form a silica xerogel within the capillary, followed by bonding of the stationary-phase group alternatively, the separation medium itself may be polymerized in situ. [Pg.167]

In capillary electrochromatography (CEC) a liquid flow through a packed capillary is created by appHcation of an electric field. Several interfaces have been designed for coupHng to ESI-MS, and current appHcations have been reviewed [93, 94]. CEC is a good alternative for neutral analytes in combination with mass spectrometric detection, since no interferences with miceUular matrix can occur [95]. The combination with LC, resulting in an electrically and a pneumatically driven flow of solvent, has been called pressurised CEC. This combination offers new opportunities for the separation of complex mixtures. [Pg.348]

Sukas S, Malsche WD, Desmet G, Gardeniers HJGE (2012) Performance evaluation of different design alternatives for microfabricated nonporous fused silica pillar columns for capillary electrochromatography. Anal Chem 84 9996-10004... [Pg.1902]

Mistry K, Krull I, and Grinberg N (2002) Capillary electrochromatography an alternative to HPLC and CE. Journal of Separation Science 25 935-958. [Pg.345]

DGE a AC AMS APCI API AP-MALDI APPI ASAP BIRD c CAD CE CF CF-FAB Cl CID cw CZE Da DAPCI DART DC DE DESI DIOS DTIMS EC ECD El ELDI EM ESI ETD eV f FAB FAIMS FD FI FT FTICR two-dimensional gel electrophoresis atto, 10 18 alternating current accelerator mass spectrometry atmospheric pressure chemical ionization atmospheric pressure ionization atmospheric pressure matrix-assisted laser desorption/ionization atmospheric pressure photoionization atmospheric-pressure solids analysis probe blackbody infrared radiative dissociation centi, 10-2 collision-activated dissociation capillary electrophoresis continuous flow continuous flow fast atom bombardment chemical ionization collision-induced dissociation continuous wave capillary zone electrophoresis dalton desorption atmospheric pressure chemical ionization direct analysis in real time direct current delayed extraction desorption electrospray ionization desorption/ionization on silicon drift tube ion mobility spectrometry electrochromatography electron capture dissociation electron ionization electrospray-assisted laser desorption/ionization electron multiplier electrospray ionization electron transfer dissociation electron volt femto, 1CT15 fast atom bombardment field asymmetric waveform ion mobility spectrometry field desorption field ionization Fourier transform Fourier transform ion cyclotron resonance... [Pg.11]