Cancer chronic alcohol consumption

The problems of alcohol dependence and alcoholism are dealt with in Chapter 10. Suffice it to say here that problem drinkers risk numerous psychological problems, such as anxiety and depression, and may experience physical withdrawal symptoms. There are also numerous medical problems related to heavy, chronic alcohol consumption these include increased risk of coronary heart disease, liver cirrhosis, impotence and infertility, cancer and stroke (Chapter 10). It is estimated that alcohol plays a part in up to 33,000 deaths per year in the UK (DoH, 2001). Within the last year 1 in 4 adults will have experienced loss of memory following an alcoholic binge, injured themselves or... 

Teschke, R., Minzlaff, M., Oldiges, H., and Frenzel, H., 1982, Effect of chronic alcohol consumption on tumor incidence due to dimethylnitrosamine administration, /. Cancer Res. Clin. Oncol 106 58. 

Chronic consumption of large amounts of alcohol is associated with an increased risk of death. Deaths linked to alcohol consumption are caused by liver disease, cancer, accidents, and suicide. 

The routes and rates of ethanol oxidation vary from individual to individual. Differences in ethanol metabolism may influence whether an individual becomes a chronic alcoholic, develops alcohol-induced liver disease, or develops other diseases associated with increased alcohol consumption (such as hepatocarcinogene-sis, lung cancer, or breast cancer). Factors that determine the rate and route of ethanol oxidation in individuals include ... 

Chronic pancreatitis has long been thought to be mainly associated with immoderate alcohol consumption, tobacco smoke, and obesity, diets high in animal protein and fat, as well as antioxidant deficiencies. Diets high in processed or red meat, diets low in fruits and vegetables, phytochemicals such as lycopene and flavonols, have been proposed and refuted as risk or protective factors in different trials [131]. In a case-control study of 462 cases and 4,721 controls, there was a significant inverse association between lycopene intake and pancreatic cancer, after... 

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